| 杨瑞杰,王皓,刘路,等.一种侧卧位X射线分次全身照射技术及剂量监测结果分析[J].中华放射医学与防护杂志,2016,36(6):435-438.Yang Ruijie,Wang Hao,Liu Lu,et al.A fractionated X-ray total body irradiation technique with patients lying on side and in vivo dosimetry analysis[J].Chin J Radiol Med Prot,2016,36(6):435-438 |
| 一种侧卧位X射线分次全身照射技术及剂量监测结果分析 |
| A fractionated X-ray total body irradiation technique with patients lying on side and in vivo dosimetry analysis |
| 投稿时间：2016-01-13 |
| DOI：10.3760/cma.j.issn.0254-5098.2016.06.007 |
| 中文关键词: X射线 全身照射 多通道半导体剂量计 剂量监测 |
| 英文关键词:X-rays Total body irradiation Multi-channel diode dosimeter Dose monitoring |
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| 中文摘要: |
| 目的 报道一种侧卧位前后对穿X射线分次全身照射技术,并对照射中的实时剂量监测结果进行分析。方法 采用Varian Trilogy医用电子直线加速器10 MV X射线,行水平野对穿全身照射,源到模体表面距离390 cm,测量X射线全身照射条件下的射野百分深度剂量、离轴剂量分布及绝对剂量输出。对10例患者采用侧卧位前后对穿野分次全身照射。照射处方剂量1200 cGy/6次,共3 d,体中线剂量率约5.0 cGy/min。治疗时利用多通道半导体剂量计实时监测患者剂量准确性及剂量分布均匀性,采用固体水进行剂量非均匀性补偿。结果 治疗条件下模体测量射野离轴剂量分布均匀性<±5.0%,最大剂量点处绝对剂量输出为0.0721 cGy/MU。10例患者均能够顺利完成侧卧位治疗,各个部位监测总剂量偏离处方剂量-4.9%~6.7%,平均监测剂量均匀性<5.0%。结论 侧卧位X射线全身分次照射技术患者耐受性好,照射过程中实时监测剂量,采用固体水进行剂量非均匀性补偿,能够保证患者接受准确均匀的剂量分布,方法简便易行。 |
| 英文摘要: |
| Objective To investigate an X-ray total body irradiation (TBI) technique using anterior-posterior opposed fields with patients at the side-lying position, and to analyze the real-time in vivo dosimetry results. Methods The accelerator with 10 MV X-rays of Varian Trilogy was used for the TBI with the extended source to skin distance of 390 cm. The percent depth dose, off axis factors and absolute dose output were measured. The dose accuracy and homogeneity was monitored real-time using multi-channel diode dosimeter for 10 patients. The monitored sites included forehead, mandible, suprasternal fossae, xiphoid, umbilicus, pelvis, middle of thigh, knee, middle of leg and ankle. The patients were irradiated at the side-lying position, with the prescription dose of 1200 cGy/6 f during 3 days, the middle line dose rate of 5.0 cGy/min. Solid water was used for the compensation of the dose homogeneity. Results The off axis dose homogeneity was less than ±5.0% for the TBI geometry. The absolute dose output was 0.0721 cGy/MU at the maximum dose point. The total body irradiation was finished smoothly for the 10 patients lying on side. The deviation of monitored total dose from the total prescription dose was within -4.9% to 6.7% for the 10 monitored sites. The monitored dose homogeneity was less than 5.0%. Conclusions The fractionated anterior-posterior opposed parallel TBI can be finished smoothly with patients side-lying. Accurate and homogenous dose distribution can be obtained using real-time dose monitoring and compensation with solid water. |
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