| 庄婷婷,林柏翰,李东升,吴丽丽.有无均整器模式下脊柱转移瘤立体定向放疗计划的剂量学比较[J].中华放射医学与防护杂志,2016,36(1):63-66 |
| 有无均整器模式下脊柱转移瘤立体定向放疗计划的剂量学比较 |
| Dosimetric comparison of stereotactic body radiation therapy plans for spine metastasis using flattening filter free and flattening filter modes |
| 投稿时间：2015-09-02 |
| DOI：10.3760/cma.j.issn.0254-5098.2016.01.012 |
| 中文关键词: 脊柱转移瘤 立体定向放疗 无均整模式 剂量学 |
| 英文关键词:Spine metastasis Stereotactic body radiation therapy Flattening filter free Dosimetry |
| 基金项目: |
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| 摘要点击次数: 2631 |
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| 中文摘要: |
| 目的 比较 6 MV X射线无均整器模式(FFF)和均整器模式(FF)下,脊柱转移瘤立体定向放疗(SBRT)计划的剂量学差异。方法 选取9例入组患者共12处脊柱转移灶分别设计FFF-SBRT和FF-SBRT计划,比较两组计划的靶区、危及器官和正常组织剂量体积直方图(DVH)、靶区适形度(CI)、机器跳数和治疗时间的差别。结果 两种模式下的计划均能满足临床治疗需要。靶区、危及器官、正常组织剂量分布相似。FFF-SBRT计划的机器跳数明显高于FF-SBRT计划(t=-5.20,P<0.01),实际治疗时间相当于FF-SBRT计划的1/2(t=17.27,P<0.01)。结论 两种模式均能满足临床治疗需求,FFF-SBRT计划的治疗时间更短,效率更高。临床试验注册中国临床试验注册中心,ChiCTR-TRC-14004281。 |
| 英文摘要: |
| Objective To compare the dosimetric difference of stereotactic body radiation therapy (SBRT) plans for spine metastasis using 6 MV X-ray flattening filter free (FFF) and flattening filter (FF) modes. Methods A total of nine previously treated patients with a total of twelve spine metastasis were retrospectively included and replanned using FFF-SBRT and FF-SBRT, respectively. The dose-volume histograms (DVH), target conformity index (CI), monitor unites (MUs) and treatment time of target volume, organs at risk and normal tissues were compared between the plans. Results Both FFF-SBRT and FF-SBRT met the clinical objectives. Dose distribution of target volume, organs at risk and normal tissues were similar. MUs of the FFF-SBRT were significantly higher than that of FF-SBRT (t=-5.20, P<0.01), while the treatment time was almost half of the latter (t=17.27, P<0.01). ConclusionsTwo plan modes are both clinically acceptable. FFF-SBRT plans are delivered in less time and with better efficiency. Trial registration Chinese clinical trial registry, ChiCTR-TRC-14004281. |
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