| 卢峰,宋钢,毕明卫,等.γ刀不同聚焦方式形成的辐射野比较[J].中华放射医学与防护杂志,2015,35(5):384-388.Lu Feng,Song Gang,Bi Mingwei,et al.Comparison of radiation field irradiated by different focusing modes of γ-knife[J].Chin J Radiol Med Prot,2015,35(5):384-388 |
| γ刀不同聚焦方式形成的辐射野比较 |
| Comparison of radiation field irradiated by different focusing modes of γ-knife |
| 投稿时间：2014-10-13 |
| DOI：10.3760/cma.j.issn.0254-5098.2015.05.018 |
| 中文关键词: γ刀 辐射野 聚焦方式 剂量 |
| 英文关键词:γ-knife Radiation field Focusing mode Dose |
| 基金项目:山东省科技发展计划(2009GG10002051) |
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| 摘要点击次数: 3399 |
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| 中文摘要: |
| 目的 比较γ刀3种聚焦方式形成的单靶点辐射野,探讨提高放射治疗剂量准确性的方法. 方法 使用EBT3型免冲洗胶片测量γ刀多源静态聚焦、多源单轴线旋转聚焦和单源双轴线旋转聚焦方式形成的单靶点辐射野,对辐射野剂量分布的均匀性和辐射野半影关系进行比较分析.结果 3种聚焦方式形成的单靶点二维等剂量曲线分布不同.轴线(x、y和z轴)上,多源静态聚焦、多源单轴线旋转聚焦与单源双轴线旋转聚焦形成的半影轴长比范围,依次为0.13~0.48、0.17~0.33和0.28~0.54;翅膀平面的对角线(NSD、PSD)上,依次为0.31~0.39、0.38~0.43和0.54~0.72,单源双轴线旋转聚焦方式形成的半影轴长比明显大于多源静态聚焦和多源单轴线旋转聚焦方式.非翅膀平面上,多源静态聚焦、多源单轴线旋转聚焦与单源双轴线旋转聚焦形成的辐射野80%剂量曲线与50%剂量曲线包绕面积比(A80%/A50%)依次为0.40、0.47和0.19;翅膀平面上,依次为0.61、0.53和0.35.多源静态聚焦和多源单轴线旋转聚焦方式形成的辐射野剂量分布均匀性优于单源双轴线旋转聚焦方式.结论 从单靶点辐射野吸收剂量分布角度考虑,当靶区周围有重要的组织器官时,宜选择使用多源静态聚焦和多源单轴线旋转聚焦方式的γ刀;多源静态聚焦和多源单轴线旋转聚焦方式相对于单源双轴线旋转聚焦方式,能够使更多的肿瘤组织被高剂量曲线所包绕. |
| 英文摘要: |
| Objective To compare the single-shot fields irradiated by three focusing modes of γ-knife and explore the approaches for improving the quality of stereotactic radiosurgery. Methods GAFCHROMIC® EBT3 mode flushing-free film was used to measure the single-shot fields irradiated by multi-source static focusing modes, multi-source single-axis rotating focusing mode and single-source double-axis rotating focusing mode of γ-knife. Also the uniformity and penumbra of the single-shot fields were compared. Results The 2D dose distribution of the single-shot fields irradiated by three focusing modes of γ-knife was different. In the axis (x, y, z), the rang of penumbra axial length ratios of multi-source static focusing modes, multi-source single-axis rotating focusing mode and single-source double-axis rotating focusing mode were 0.13-0.48, 0.17-0.33 and 0.28-0.54, in the diagonal direction of the wings plane (NSD, PSD), were 0.31-0.39,0.38-0.43 and 0.54-0.72, respectively; the penumbra axial length ratio of single-source double-axis rotating focusing mode was bigger than in multi-source static focusing modes and multi-source single-axis rotating focusing mode. On the no-wings plane, the area ratios of 80% dose curve enveloped and 50% dose curve enveloped(A80%/A50%)were 0.40,0.47 and 0.19, on the wings plane, were 0.61,0.53 and 0.35, respectively. The field uniformity of multi-source static focusing modes and multi-source single-axis rotating focusing mode were superior to single-source double-axis rotating focusing mode. Conclusions Considering dose distribution of the single-shot fields, the multi-source static focusing modes devices and the multi-source single-axis rotating focusing mode devices should be preferred, when important tissues and organs are adjacent to the target areas. Compared with single-source double-axis rotating focusing mode, both multi-source static focusing modes and multi-source single-axis rotating focusing mode could make more target areas to be surrounded by high dose region. |
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