| 曹国全,许化致,潘克华,陈伟建,郭翔.320排容积CT全脑灌注成像扫描协议优化研究[J].中华放射医学与防护杂志,2014,34(5):386-389 |
| 320排容积CT全脑灌注成像扫描协议优化研究 |
| Optimizing the scan protocol in whole-brain perfusion imaging with 320-MDCT |
| 投稿时间：2013-07-25 |
| DOI：10.3760/cma.j.issn.0254-5098.2014.05.018 |
| 中文关键词: 体层摄影术 辐射剂量 全脑CT灌注 扫描协议 |
| 英文关键词:Tomography Radiation dose Whole brain CT perfusion Scan protocol |
| 基金项目:温州市科技局科技计划项目（Y20130146） |
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| 全文下载次数: 2012 |
| 中文摘要: |
| 目的 探讨320排容积CT全脑灌注成像扫描协议优化的可行性。方法 20名健康志愿者按随机数字表法分为对照组和试验组，对照组7例，选择标准灌注扫描协议（19圈容积采集）；试验组13例，通过合理改变采集间隔，减少扫描期相，采用一组新的灌注扫描协议（11圈容积采集）。图像分析感兴趣区（ROI）设为两侧额叶白质、顶叶白质、半卵圆区、基底节区、枕叶、小脑，大小约（20±2）mm2。计算得到各感兴趣区的灌注参数值，包括脑血容量（rCBV）、达峰时间（TTP）、脑血流量（rCBF）、平均通过时间（MTT）及延迟时间（DT）。结果 试验组剂量长度乘积（DLP）和有效剂量（E）较对照组降低了42.02%。两组不同层面左右两侧ROI区的各灌注参数的差异无统计学意义。两组组间上述各个对应部位的ROI区各灌注参数无明显差别。结论 优化后的扫描协议得到了与厂家推荐的标准协议无差异的全脑灌注参数值且降低了辐射剂量，推荐常规使用。 |
| 英文摘要: |
| Objective To evaluate the feasibility of optimized scan protocol in whole-brain perfusion imaging with 320-MDCT scanner.Methods Twenty healthy volunteers were randomly divided into control group (13 patients) and test group (7 patients).The standard perfusion scan protocol(collecting 19 volumes)was applied in control group.The optimized perfusion CT scan protocol(collecting 11 volumes)formulated by reducing scanning phases reasonably and changing the collection intervals was applied in test group.The regions of interest(ROI)with area of(20±2)mm2 were located in the bilateral frontal white matter, parietal white matter, centrum semiovate, basal ganglia, occipital lobe and cerebellum.Bilateral perfusion values from ROI were measured, including cerebral blood volume(CBV), mean transit time(TTP), cerebral blood flow(CBF), mean transit time(MTT)and delay time(DT).Results Dose length product(DLP)and effective dose(ED)in optimized protocol were decreased 42.02% as compared to control group.Every relative perfusion value of both sides from both groups were not statistically significant (P> 0.05).Every relative perfusion parameters from individual territory in both groups showed no significant differences (P> 0.05).Conclusions Using the optimized scan protocol, we could obtain the same whole-brain perfusion values could be obtained with the default standard protocol and less radiation dose. |
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