| 张宏涛,唐富龙,吴立丽,等.计算点阵网格大小对125I粒子植入剂量计算精度的影响[J].中华放射医学与防护杂志,2014,34(1):59-61.Zhang Hongtao,Tang Fulong,Wu Lili,et al.Effect of TPS calculating grid on dose calculation accuracy for 125I seed implantation[J].Chin J Radiol Med Prot,2014,34(1):59-61 |
| 计算点阵网格大小对125I粒子植入剂量计算精度的影响 |
| Effect of TPS calculating grid on dose calculation accuracy for 125I seed implantation |
| 投稿时间：2013-06-05 |
| DOI：10.3760/cma.j.issn.0254-5098.2014.01.016 |
| 中文关键词: 125I粒子 近距离治疗 剂量 |
| 英文关键词:125I seed Brachytherapy Dose |
| 基金项目:河北省科学技术厅支撑项目（11276103D-34） |
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| 中文摘要: |
| 目的 观察 125I 粒子植入时，计算机治疗计划系统（TPS）软件中计算点阵网格大小对剂量计算精度的影响。方法 采用随机数字表法抽取10例粒子植入患者的验证计划，将点阵网格调整为128×128、96×96、64×64、32×32共4组，在粒子数目、位置、活度及靶区大小相同的条件下，应用TPS计算每个计划的剂量，分别得出4组D90、V90、V100及V150，并计算D90的误差。结果 128×128、96×96、64×64、32×32 4组点阵网格D90平均数分别为（7 178.8±2 237.7）、（7 072.7±2 240.8）、（6 889.1±2 305.5）、（6 351.0±2 515.7）cGy；D90误差百分比分别为（0.74±0.6）%、（-0.89±2.2）%、（-3.85±4.7）%、（-10.46±4.8）%，组间差异有统计学意义（F=8.95，P<0.05）。4组点阵网格V90分别为（93.12±0.32）%、（92.75±0.29）%、（91.87±1.28）%、（88.06±5.06）%，组间差异有统计学意义（F=7.85，P<0.05）；V100分别为（90.21±0.14）%、（89.67±0.64）%、（88.68±1.80）%、（84.10±6.56）%，组间差异有统计学意义（F=6.64，P<0.05）；V150分别为（73.48±3.49）%、（72.66±3.96）%、（71.33±4.83）%、（65.41±9.49）%，组间差异有统计学意义（F=3.90，P<0.05）。结论 计算点阵网格大小明显影响TPS计算剂量的准确性，在保证运算速度同时应尽量应用128×128的计算点阵网格。 |
| 英文摘要: |
| Objective To study the influence of TPS calculation grid on the dose calculation accuracy for 125I seed implantation. Methods Ten verification plans were selected randomly. Calculating grids were modulated into four groups: 128×128, 96×96, 64×64 and 32×32. Under the conditions of same seeds number, location, activity and target volume, the doses resulting from every plan were calculated using TPS to obtain D90,V90, V100 and V150. Data were grouped into A, B, C and D by means of the calculating grid of 128×128, 96×96, 64×64 and 32×32. The percentage errors of four groups were calculated. Results The arithmetic mean D90 of group A, B, C and D were(7 178.8±2 237.7), (7 072.7±2 240.8), (6 889.1±2 305.5) and (6 351.0±2 515.7)cGy, respectively. The arithmetic mean of percentage errors of the four groups were(0.74±0.6)%, (-0.89±2.2)%, (-3.85±4.7)% and (-10.46±4.8)% (F=8.95, P<0.05). The V90 of group A, B, C and D were (93.12±0.32)%, (92.75±0.29)%, (91.87±1.28)% and (88.06±5.06)%(F=7.85, P<0.05). The V100 of group A, B, C and D were (90.21±0.14)%, (89.67±0.64)%, (88.68±1.80)% and (84.10±6.56)%(F=6.64, P<0.05). The V150 of group A, B, C and D were (73.48±3.49)%, (72.66±3.96)%, (71.33±4.83)% and (65.41±9.49)% (F=3.90,P<0.05). Conclusions The dose calculating accuracy of 125I seeds implantation is influenced significantly by TPS calculating grid. The calculating grid of 128×128 should be used as long as the calculating speed is not reduced. |
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