| 姜晶,孔婷,黄波,周平坤,让蔚清.低剂量电离辐射对放射工作人员眼晶状体影响的Meta分析[J].中华放射医学与防护杂志,2013,33(6):640-644 |
| 低剂量电离辐射对放射工作人员眼晶状体影响的Meta分析 |
| Effect of low-dose radiation on ocular lens of radiation workers：Meta-analysis |
| 投稿时间：2013-04-10 |
| DOI：10.3760/cma.j.issn.0254-5098.2013.06.019 |
| 中文关键词: 放射工作人员 电离辐射 晶状体混浊 Meta分析 |
| 英文关键词:Radiation workers Ionizing radiation Lens opacity Meta-analysis |
| 基金项目:国家863项目（2012AA063501）；国家自然科学基金（81272994） |
|
| 摘要点击次数: 3343 |
| 全文下载次数: 2424 |
| 中文摘要: |
| 目的 综合分析长期低剂量电离辐射对放射工作人员眼晶状体的影响。方法 检索国内外相关数据库，辅以查阅文献，查找1990—2013年发表的关于职业照射对放射工作人员晶状体影响的文献。最终纳入Meta分析的中外文文献28篇，总研究对象数17 608人。用Stata 12.0软件做Meta分析，异质性检验用Q检验和I2统计量，发表偏倚识别用漏斗图、Begg秩相关法和Egger线性回归法。结果 放射工作人员眼晶状体混浊和晶状体后囊下混浊的合并比值比及其95%的可信区间分别为2.51（2.01，3.13）和4.03（2.77，5.85）。结论 在目前的职业防护状况下，低剂量电离辐射对放射工作人员眼晶状体可造成不良影响，且晶状体后囊下混浊所占比重上升，应加强眼晶状体的辐射防护。 |
| 英文摘要: |
| Objective To comprehensively analyze the effect of low-dose radiation on the lens of the eye of radiation workers. Methods The papers dealing with the relationship between occupational radiation exposure and the lens of the eye were collected by retrieving documents of the domestic and foreign medical information databases with references to other papers. There were 28 papers finalized with 17 608 workers included in the Meta-analysis. Stata12.0 was used for Meta-analysis, Q-test and I2 statistic for heterogeneity test, and funnel regression method, Begg's rank method and Egger's regression method for publication bias. Results The pooling odds ratio (OR) opacity in radiation workers were 2.51(2.01,3.13), 4.03(2.77,5.85), respectively. Conclusions Low-dose radiation may lead to negative impact on ocular lens under the current occupational protection conditions. The proportion of posterior subcapsular opacity in radiation-related cataract is higher than that in age-related cataract. It is important to strengthen radiation protection of ocular lens. |
| HTML 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |