夏巍,吴晶涛,尹肖睿,等.数字合成体层成像低剂量特性在骨骼系统影像学中的研究[J].中华放射医学与防护杂志,2012,32(6):656-659.XIA Wei,WU Jing-tao,YIN Xiao-rui,et al.Study of low radiation characteristics of digital tomosynthesis in diagnostic imaging of skeletal system[J].Chin J Radiol Med Prot,2012,32(6):656-659 |
数字合成体层成像低剂量特性在骨骼系统影像学中的研究 |
Study of low radiation characteristics of digital tomosynthesis in diagnostic imaging of skeletal system |
投稿时间:2012-03-28 |
DOI:10.3760/cma.j.issn.0254-5098.2012.06.028 |
中文关键词: 辐射剂量 数字化断层融合技术 数字X射线摄影 电子计算机X射线断层扫描技术 骨骼系统 |
英文关键词:Radiation dose DTS DR CT Skeletal system |
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中文摘要: |
目的 对比数字化断层融合技术(DTS)与数字X射线摄影(DR)、电子计算机X射线断层扫描技术(CT)在骨骼系统影像学诊断中X射线辐射剂量的差异,分析3种检查方法在骨骼系统影像学诊断中的敏感性、特异性。方法 回顾性分析2010年2月至2012年3月间在本院同时行DR、DTS、CT骨骼系统检查的100名患者资料,对比DR、DTS、CT之间的X射线辐射剂量,以临床诊断结果为金标准,由2名专家评价3种检查方法的图像,对评价结果进行受试者操作特性曲线(ROC)分析。结果 DR、DTS、CT组的吸收剂量与有效剂量平均值分别为[(1.9±1.8)mGy、(0.03±0.03) mSv)]、[(3.5±1.5)mGy、(0.05±0.02) mSv)]、[(397.7±106.0)mGy·cm、(5.60±1.50) mSv]。3种检查方法的吸收剂量和有效剂量差异有统计学意义(F=1377、 1377,P<0.05)。采用LSD检验分析CT与DR、DTS的辐射剂量,差异有统计学意义(P<0.05)。阅片者A、B对DR、DTS、CT检出病灶可信度评价的ROC曲线下面积分别为0.870±0.035、0.966±0.018、0.974±0.015和0.852±0.038、0.951±0.021、0.959±0.019,对其进行Z检验,DR与DTS的差异有统计学意义(P<0.05);DR与CT的差异有统计学意义(P<0.05)。CT与DR敏感性差异有统计学意义(χ2=4.833,P<0.05)。结论 DTS的辐射剂量只有CT的1%左右,其在骨骼系统的图像质量可以与CT相当。如有DR检查诊断不明确或有疑似病变的患者,推荐首选DTS进一步检查,减少不必要的辐射剂量。 |
英文摘要: |
Objective To investigate the radiation dose differences of DTS, DR and CT in diagnostic imaging of the skeletal system and analyze the sensitivity and specificity of each modality in skeletal disease diagnosis. Methods 100 relevant patients with skeletal diseases were randomly selected, who were performed with DR, DTS and CT from Feb 2010 to Mar 2012. They were divided into three groups, respectively as the DR group, the DTS group and the CT group. The complete information including DR, DTS, CT data and the final clinical diagnosis were collected and the statistical analysis after comparing radiation dose of DR, DTS and CT examination. Two experienced experts evaluated the image of three examinations and made judgments. ROC curves of reader A and B were made by using the final clinical diagnosis as gold standard. Results The average absorbed dose and effective dose of DR, DTS, CT group were [(1.9±1.8)mGy, (0.03±0.03) mSv)], [(3.5±1.5)mGy, (0.05±0.02) mSv)], [(397.7±106.0)mGy·cm、(5.60±1.50) mSv] respectively. The difference among the three groups was analyzed by one-way ANOVA test(F=1377, P<0.05) and had statistically significant(P<0.05). ROC curve was drawn through analyzing lesion detection credibility of three groups. The AZ values of reader A and B was(0.870±0.035,0.966±0.018,0.974±0.015)and(0.852±0.038,0.951±0.021,0.959±0.019)respectively. Do the Z-test to these examinations’ area under ROC curve of lesion detection credibility. Between DR and DTS or DR and CT, there was statistically significant(P<0.05). While for CT and DTS, there was not statistically significant. The two readers’ sensitivity and specificity in diagnosing skeletal lesion with DR, DTS and CT were investigated using the χ2 test: CT and DTS were no statistical significance, CT and DR were statistically significant(χ2=4.833,P<0.05). Conclusions Radiation dose of DTS only accounts for about 1% of CT examination. While its sensitivity and specificity can meet the requirements for clinical diagnosis as CT. If the DR diagnosis is unclear or suspected, DTS should be the first recommended modality used for skeletal diagnosis with lower radiation dose. |
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