| 韩林,赵风玲,王喜爱,等.七例疑似受照的医疗工作人员染色体畸变分析[J].中华放射医学与防护杂志,2012,32(6):607-609.HAN Lin,ZHAO Feng-ling,WANG Xi-ai,et al.Analysis of chromosomal aberration in seven medical staffs suspected with exposure to ionizing radiation[J].Chin J Radiol Med Prot,2012,32(6):607-609 |
| 七例疑似受照的医疗工作人员染色体畸变分析 |
| Analysis of chromosomal aberration in seven medical staffs suspected with exposure to ionizing radiation |
| 投稿时间：2012-04-09 |
| DOI：10.3760/cma.j.issn.0254-5098.2012.06.011 |
| 中文关键词: 电离辐射 医疗工作人员 染色体畸变 |
| 英文关键词:Ionizing radiation Medical staff Chromosomal aberration |
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| 中文摘要: |
| 目的 通过对怀疑受到电离辐射照射的医疗工作人员进行外周血淋巴细胞染色体畸变分析,探讨可能的受影响因素。方法 某医院检验科工作人员7名,男性1名,女性6名。他们工作室的楼下是医院CT室,工作室和CT室间的楼板为厚度约6 cm的普通预制板。采用常规法,对7名人员外周血淋巴细胞染色体畸变进行分析。结果 4例女性工作人员外周血中检测到双着丝粒体(dic),dic率为0.40%~1.60%,明显高于dic的自发率(0.03%, χ2=36.79, P<0.05);在所有工作人员中均检测到易位畸变,易位率在0.33%~1.20%之间,明显高于易位的自发率(0.01%,χ2=42.90, P<0.05)。结论 推测这些工作人员受到过量电离辐射照射。 |
| 英文摘要: |
| Objective To investigate the chromosomal aberrations in seven medical staffs suspected with exposure to ionizing radiation and to speculate its possible causation. Methods The hospital staffs, including 6 females and 1 male, worked in a clinical laboratory where a CT room was located downstairs. The thickness of precast slab between these two rooms was 6 cm. Peripheral blood lymphocytes of seven staffs were examined for conventional chromosomal aberrations. Results The frequencies of dicentrics in the peripheral lymphocytes of 4 females were from 0.40% to 1.60% that was significantly higher than the spontaneous frequency of dicentrics (0.03%, χ2=36.79, P<0.05). The translocation was observed in the lymphocytes from all subjects with frequencies from 0.33% to 1.20%, obviously higher than its spontaneous frequency of 0.01% (χ2=42.90, P<0.05). Conclusion These staffs suffer from ionizing radiation. |
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