何志坚,袁继龙,高磊,罗素明,邱杰,杨波,庞庭田.二极管半导体探测器(Diode)测量放射治疗患者剂量方法的研究[J].中华放射医学与防护杂志,2011,31(3):355-358
二极管半导体探测器(Diode)测量放射治疗患者剂量方法的研究
Development of the Diode method for patient's dose measurement in radiotherapy
投稿时间:2010-02-22  
DOI:10.3760/cma.j.issn.0254-5098.2011.03.029
中文关键词:  二极管半导体探测器  治疗计划系统  光子线束  放射治疗  剂量
英文关键词:Diode  Treatment planning system  Photon beam  Radiotherapy  Dose
基金项目:IAEA资助项目(13114/R0)
作者单位
何志坚 100088 北京,中国疾病预防控制中心辐射防护与核安全医学所 
袁继龙 100088 北京,中国疾病预防控制中心辐射防护与核安全医学所 
高磊 100088 北京,中国疾病预防控制中心辐射防护与核安全医学所 
罗素明 100088 北京,中国疾病预防控制中心辐射防护与核安全医学所 
邱杰 北京协和医院 
杨波 北京协和医院 
庞庭田 北京协和医院 
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中文摘要:
      目的 研究用Diode探测器测量光子线束治疗中患者接受剂量的方法,验证治疗计划系统(TPS)计算剂量,并与Diode探测器测量剂量进行比较。方法 60Co γ射线、6 MV X射线、水模体和固体模体,开展Diode探测器的重复性、剂量率响应、非线性剂量响应及刻度因子等实验。根据临床治疗需要,选择在不同条件下,研究剂量随机器角度、能量响应、源皮距、照射野、楔形角度、挡块和托盘因子等变化的影响,求出Diode探测器校准因子,用仿真人模体、Diode探测器、6 MV X线束,验证骨盆、头颈等部位剂量。再用Diode探测器测量6 MV X射线照射9例放疗患者的头颈、胸及腹等部位的剂量。结果 仿真人模体骨盆前面,左、右两侧(加楔形和不加楔形角度),以及头颈部左、右两侧(戴面具和不带面具)条件下,Diode测量值与TPS计算值的相对偏差均在±3%以内;放疗患者的头颈部两侧(戴面具)、胸部及腹部,Diode测量值与TPS计算值的相对偏差均在±5%以内。结论 用Diode探测器验证放疗患者剂量方法准确可靠,能快速获得数据。
英文摘要:
      Objective To explore the measurement method of the treatment dose of the patient with Diode for photon beam in radiotherapy,and to validate the treatment dose by comparing with the treatment planning system (TPS). Methods Experiments of the reproducibility, dose rate dependence, non-linearity dose response, and calibration factor in 60Co γ and 6 MV X beams were carried out with Diode on the surface of solid phantom and in water phantom. According to the needs of clinic treatment, different conditions were chosen to observe the dose changes with the angle of incidence, energy response, distance of source to skin, field size, wedge angle, block and tray using ionization chamber and water phantom. The Diode was placed on the surface of the solid phantom to obtain the correction factors. The doses of the chest, abdomen, and head and neck were verified with the Alderson phantom and Diode. Diode doses of the pelvis, head and neck at 14 points on the patient were measured. Results The Diode was irradiated at the points of the Alderson phantom, such as AP, RL and LL of the pelvis, with and without wedges, RL and LL junction of the neck and chin, with and without mask, the maximum relative deviation of doses was within ±3% between Diode and TPS. The Diode was placed in different locations on the patient, including chest, abdomen and head and neck. The relative maximum deviation of doses was within ±5% between Diode and TPS. Conclusions The Diode method is reliable for measuring the exposure doses of the patient in radiotherapy.
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