廖美焱,周云峰,徐丽莹,胡慧娟,曹毅媛,彭碧荣.低剂量技术降低CT引导下经皮肺切割活检吸收剂量的临床研究[J].中华放射医学与防护杂志,2010,30(1):82-85
低剂量技术降低CT引导下经皮肺切割活检吸收剂量的临床研究
Dose reduction using in CT-guided lung automated cutting needle biopsy
投稿时间:2009-06-13  
DOI:
中文关键词:  活组织检查  CT引导  肺病变  辐射防护
英文关键词:Biopsy  CT guidance  Pulmonary lesions  Radioprotection
基金项目:
作者单位E-mail
廖美焱 430071 武汉大学中南医院放射科  
周云峰 武汉大学中南医院放射科, 放疗科 yunfeng_zhou@hotmail.cn 
徐丽莹 430071 武汉大学中南医院放射科  
胡慧娟 430071 武汉大学中南医院放射科  
曹毅媛 430071 武汉大学中南医院放射科  
彭碧荣 430071 武汉大学中南医院放射科  
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中文摘要:
      目的 探讨临床应用低剂量技术降低CT引导下经皮肺穿刺自动切割活检(ACNB)辐射剂量的可行性。方法 412例ACNB中146例(A组)采用传统方法引导,266例(B组)采用低剂量技术引导,按图像颗粒均匀性、解剖结构细节、界面清晰度和有无伪影等评定图像质量,比较2组穿刺活检准确率、操作时间及辐射剂量,并探讨CT引导中降低辐射剂量的方法。结果 B组图像解剖结构细节分辨率降低,但不影响穿刺成功率。A、B组穿刺准确率分别为95.9%、95.1%,操作时间为(16±2.2)、(15.9±2.0)min,组间差异均无统计学意义。A、B组有效剂量为(1.74±0.7)及(0.59±0.14)mSv,B组有效剂量降低66%,差异有统计学意义(t=19.3415,P(0.05)。结论 CT引导下经皮肺穿刺活检是诊断和鉴别肺部病变的重要方法,低剂量扫描、缩小扫描范围及减少扫描次数能显著降低受检者X线辐射剂量,但不影响诊断效果。
英文摘要:
      Objective To evaluate the dose reduction technology using in CT-guided percutaneous lung biopsy of pulmonary lesions using automated core needle biopsies (ACNB). Methods 412 ACNB cases included 146 consecutive conventional patients (group A, 120 kV/100 mA) and 266 consecutive patients (group B, 120 kV/20 mA, low-dose scanning, reduce scanning width and scanning frequency). The quality of images was compared by grain homogeneity, fine structure, clearness of tissue interface and artifacts. The total diagnostic accuracy rate, the examination time and radiation dose between group A and group B were compared. Results The fine structure of group B was significantly lower ( χ2 =7.0508, P ﹤0.05). The total diagnostic accuracy rate was 95.9% vs 95.1% ( χ2 =0.1296, P ﹤0.05). The examination time for biopsy procedure was (16±2.2)min vs (15.9±2.0)min ( t =1.3579, P ﹤0.05), and the mean effective dose (E) was (1.74±0.7) mSv vs (0.59±0.14) mSv ( t =19.3415, P ﹤0.05). The E of group B decreased by 66%. Conclusions ACNB is a feasible and accurate method for diagnosing pulmonary lesions, and the E can significantly reduce the dose received in low-dose scanning.
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