| 段玉龙,范向辉,史中州,等.立体定向分次放疗联合全脑放射治疗脑转移瘤疗效分析[J].中华放射医学与防护杂志,2009,29(3):286-287.DUAN Yu-long,FAN Xiang-hui,SHI Zhong-zhou,et al.Clinical analysis of X-knife under fractionational stereotactic radiotherapy combine whole brain radioterapy for brain metastases tumor[J].Chin J Radiol Med Prot,2009,29(3):286-287 |
| 立体定向分次放疗联合全脑放射治疗脑转移瘤疗效分析 |
| Clinical analysis of X-knife under fractionational stereotactic radiotherapy combine whole brain radioterapy for brain metastases tumor |
| 投稿时间：2008-06-13 |
| DOI：10.3760/cma.j.issn.0254-5098.2009.03.012 |
| 中文关键词: 肿瘤转移 脑 立体定向放射疗法 全脑放射疗法 预后 |
| 英文关键词:Neoplasm metastais Brain \ Stereotactic radiotherapy \ Whole brain radiotherapy \ Prognosis |
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| 中文摘要: |
| 目的 分析X刀分次立体定向放疗(FSRT)联合全脑照射(WBRT)治疗脑转移瘤疗效。方法 回顾性分析51例脑转移瘤FSRT+WBRT和35例脑转移瘤单纯WBRT的结果,比较分析两者有效率、生存率的差异。结果 FSRT+WBRT、WBRT组完全缓解率分别为49%、26%(P<0.05),中位生存期分别为(11.0±1.5)、(6.5±0.5)个月(P<0.05),18个月生存率分别为24%、9%(P<0.05)。两组有效率(8%、71%,P>0.05)和6、12个月生存率(63%、41%,51%、23%,P>0.05)相似。 结论 X刀FSRT联合WBRT治疗脑转移瘤损伤小、安全、延长生存期,疗效优于单纯全颅放疗。 |
| 英文摘要: |
| Objective To evaluate efficiency of brain metastases tumor using X-knife under farctionational stereotactic radiotherapy (FSRT) combine with whole brain radiotherapy (WBRT).Methods Retrospective comparing 51 patients treated by FSRT plus WBRT (FSRT+WBRT group) with 35 patients treated by WBRT alone (WBRT group) on the effecting rate and survival rate.Results The completeness response rate was 49% and 26% (P<0.05) in FSRT+WBRT and WBRT groups, respectively. The effecting rate was 80% and 71% (P>0.05) in FSRT+WBRT and WBRT groups, respectively. The middle survival time was (11.0±1.5) months and (6.5+0.5) months (P<0.05) in FSRT+WBRT and WBRT groups, respectivley. The 0.5-,1.0- and 1.5-years survival rate was 63% and 41% (P>0.05), 51% and 23% (P>0.05) and 24% and 9% (P<0.05) in FSRT+WBRT and WBRT groups, respectively.Conclusions The method with FSRT plus WBRT in the treatment of brain metastases tumor is safe and relieved focal symptom of patients quickly with lesser injury on normal tissue and the survival time be prolonged,it has better therapeutic effects than WBRT alone for treating brain metastases tumor. |
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