| 秦岭,杨小冶,李龄,邓卓霞.电话版常识-记忆-注意测验在评价鼻咽癌患者放疗后认知功能的应用价值研究[J].中华放射医学与防护杂志,2009,29(1):84-87 |
| 电话版常识-记忆-注意测验在评价鼻咽癌患者放疗后认知功能的应用价值研究 |
| Telephone information-memory-concentration test used in evaluating cognitive function of patients with nasopharyngeal carcinoma after radiotherapy |
| 投稿时间：2008-05-09 |
| DOI：10.3760/cma.j.issn.0254-5098.2009.01.027 |
| 中文关键词: 鼻咽癌 认知功能 常识-记忆-注意测验 |
| 英文关键词:Nasopharyngeal neoplasm Cognitive function Information-memory-concentration test |
| 基金项目:广西医疗卫生重点科技项目基金资助(200520) |
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| 中文摘要: |
| 目的 评价电话版常识-记忆-注意测验(TIMCT)在鼻咽癌放疗后患者认知功能检测的应用价值。方法 对正常人(30例)和放疗结束3个月、2年、5年的鼻咽癌门诊复查患者(各30例)首先使用以往简易精神状态检查法(MMSE)和修订后的TIMCT面访,以及面访2周后再电话访问(电访)1次。结果 不以MMSE得分作为控制变量,全组TIMCT电访与TIMCT面访评分相关性较大,R=0.850;以MMSE得分作为控制变量,全组TIMCT电访与TIMCT面访评分相关性较低,R=0.366;以检测时机为分层因素作TIMCT电话访问与TTMCT面访评分的偏相关分析表明两者仅在正常人和放疗结束3个月者有相关性,放疗结束2年和5年者无相关性(R=0.447、0.970、0.200、0.062)。TIMCT电访与TTMCT面访评分差值散点图进一步表明只有当MMSE评分≥28分时电访与面访评分才会一致,但面访与电访都可以反映研究对象认知功能下降的趋势。结论 TIMCT电访与TIMCT面访、MMSE面访可以反映放疗结束后鼻咽癌门诊复查患者认知功能下降的趋势,但TIMCT电访尚须进一步改良才能应用于鼻咽癌放疗结束后认知功能损伤的临床筛查。 |
| 英文摘要: |
| Objective To investigate the telephone information-memory-concentration test (TIMCT) in evaluating the cognitive function of patients with nasopharyngeal carcinoma(NPC)after radiotherapy. Methods The cognitive function were evaluated by TIMCT and mini mental state examination (MMSE) in 2 weeks for 30 normal persons and 90 NPC patients. And the 90 NPC patients were divided into the 3 months, 2 years and 5 years after radiotherapy groups. All patients were carried out firstly face to face interview and telephone interview 1 time after 2 weeks. Results The correlation coefficient of all groups between TIMCT(telephone) and TIMCT (face to face) were bigger (R=0.850) when MMSE wasnt control variable. And the correlation coefficients between TIMCT (telephone) and TIMCT (face to face) were lower (R=0.366) when MMSE was control variable. As for examining time was classification factor, TIMCT (telephone) and TIMCT (face to face) were analyzed by partial correlation analysis. Only normal group was correlated with group of 3 months after radiotherapy and group of 2 years after radiotherapy wasnt correlated with group of 5 years after radiotherapy (R=0.447,0.970,0.200 and 0.062). In addition, the difference plot of TIMCT(telephone) and TIMCT (face to face) indicated that telephone was consistent with face to face interview (MMSE≥28). Both telephone and face to face interview reflected the cognitive function downtrend of research objects.Conclusion TIMCT (telephone), TIMCT(face to face) and MMSE (face to face) can reflect cognitive function downterend of patients with NPC after radiotherapy. But TIMCT(telephone)used in clinical screening cognitive function impairment of patients with NPC after radiotherapy should be improved further. |
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