刘玉龙,蒲汪旸,包雍镝,李元,张玉松,戴宏,周丽英,周剑影.两例131I体内、体表污染人员的医学处理[J].中华放射医学与防护杂志,2008,28(5):459-461,465
两例131I体内、体表污染人员的医学处理
Medical treatment of two cases with internal contamination combined with skin contamination of 131I
投稿时间:2008-05-08  
DOI:
中文关键词:  131I  体内污染  体表污染  剂量估算  医学处理
英文关键词:131I  Internal contamination of radionuclides  Skin contamination of radionuclides  Dose estimation  Medical treatment
基金项目:
作者单位E-mail
刘玉龙 215004 苏州大学附属第二医院 yulongliu2002@yahoo.com.cn 
蒲汪旸 215004 苏州大学附属第二医院  
包雍镝 215004 苏州大学附属第二医院  
李元 215004 苏州大学附属第二医院  
张玉松 215004 苏州大学附属第二医院  
戴宏 215004 苏州大学附属第二医院  
周丽英 215004 苏州大学附属第二医院  
周剑影 215004 苏州大学附属第二医院  
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中文摘要:
      目的 通过对2例131I体内、体表污染人员的事故经过、临床特点、剂量估算、临床救治及医学随访观察结果的报道,为类似病例的医学应急救治提供资料和经验。方法 采用全身测量装置进行放射性监测,通过INDO 2000软件进行估算剂量;医学处理包括问诊与体检、污染部位皮肤的去污洗消及综合治疗等;医学随访项目包括常规检查、肿瘤标志物检测、染色体畸变及微核分析等。结果 INDO 2000软件估算出2例事故受照人员的待积有效剂量分别为0.10~0.19Sv及0.023~0.046Sv,甲状腺的待积当量剂量分别为2.0~3.8Sv及0.46~0.89Sv。对他们进行去污洗消及综合治疗取得了较好的疗效,4年的医学随访观察未见明显异常。结论 成功地对2例131I体内、体表污染人员进行了剂量估算、医学处理及随访观察。
英文摘要:
      Objective To introduce the accident course and clinical characteristics of two cases with internal contamination combined with skin contamination of 131I, and to present the dose estimation, medical treatment and their follow-up study which will be helpful for the similar cases in medical emergency. Methods Whole body count measurement apparatus was used for radioactivity monitoring and dose was estimated and calculated by using INDO 2000 software. Medical treatment included asking and physical examination, decontamination of contaminated skins and combined therapies. The laboratory examination of routine examination, tumor markers, and conventional chromosome aberration and micronucleus analysis were included in medical follow-up. Results The committed effective doses evaluated by INDO 2000 software were 0.10-0.19 Sv and 0.023-0.046 Sv for two cases respectively. 2.0-3.8 Sv and 0.46-0.89 Sv were the committed doses equivalent of hypothyroid for them separately. Decontamination and combined therapies were effective methods and there was no obvious abnormity in a 4-year medical follow-up. Conclusions Dose estimation, medical treatment and follow-up study for two cases with an internal-and-skin combined contamination of 131I has been properly performed.
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