高磊,罗素明,邱杰,等.金属氧化物半导体场效应管探测器在放射治疗中的剂量学研究[J].中华放射医学与防护杂志,2008,28(2):184-187.GAO Lei,LUO Su-ming,QIU Jie,et al.Measurement of dose with metal oxide semi-conductor field effect transistor in radiotherapy[J].Chin J Radiol Med Prot,2008,28(2):184-187
金属氧化物半导体场效应管探测器在放射治疗中的剂量学研究
Measurement of dose with metal oxide semi-conductor field effect transistor in radiotherapy
投稿时间:2007-12-14  
DOI:
中文关键词:  金属氧化物半导体场效应管  治疗计划系统  光子线束
英文关键词:Metal oxide semi-conductor field effect transistor  Treatment planning system  Photon beam
基金项目:国际原子能机构资助项目(13114R0)
作者单位E-mail
高磊 100088 北京, 中国疾病预防控制中心辐射防护与核安全医学所  
罗素明 100088 北京, 中国疾病预防控制中心辐射防护与核安全医学所 sumingluo@163.com 
邱杰 北京协和医院  
何志坚 100088 北京, 中国疾病预防控制中心辐射防护与核安全医学所  
杨波 北京协和医院  
庞庭田 北京协和医院  
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中文摘要:
      目的 研究用金属氧化物半导体场效应管(MOSFET)探测器测量光子线束放射治疗患者的照射剂量。方法 用6 MV X线束、固体模体,开展MOSFET探测器的重复性、非线性剂量响应、剂量率和剂量水平响应实验。根据临床治疗需要,选择不同的照射条件,开展剂量随照射野、源到皮肤距离、入射角度、楔形角度、档块和托盘等变化的影响实验,分别求出校正因子。用仿真人(Alderson)模体,验证骨盆、头颈等治疗部位的剂量。选择一定数量的临床患者,测量患者在放射治疗中实际接受的剂量。结果 MOSFET探测器测量腹部和头颈部放射治疗患者42名、总剂量点644个,其中腹部放疗患者25名、测量剂量点374个,293个剂量点在相对偏差±5%以内占总剂量点的78.3%;头颈部患者17名、测量剂量点270个,233个剂量点在相对偏差±5%以内占总剂量点的86.3%。结论 用MOSFET探测器验证放射治疗中患者剂量的方法实时、便捷。该方法作为质量保证手段之一,可在开展放射治疗的医院中推荐使用。
英文摘要:
      Objective To study the measurement of the radiation doses of patient using MOSFET with photon beam in radiotherapy.Methods The experiments of reproducibility, non-linearity dose response,dependence of dose rate,and reproducibility at different dose levels were carried out with 6 MV X-ray beam by using MOSFET. According to the need in clinical treatment, the doses were selected depending on the field size, distance of source to skin, angle of incidence, energy response, wedge angle, and block and tray. The corresponding calibration factors were calculateted. The doses of the pelvis, head and neck were validated with Alderson phantom and MOSFET. 42 cases of patients were choosed to evaluate the difference between MOSFET measured dose and TPS calculated dose.Results 644 dose points were measured with MOSFET, including 374 points for abdomen radiotherapy and 270 for head and neck radiotherapy. The relative deviation was within ±5% both for 78.3% of abdomen radiotherapy and for 85.7% of head and neck radiotherapy.Conclusions MOSFET is real-time and convenient to measure the radiotherapy doses of patients. It can be used as a method for quality control and assurance of clinical radiotherapy.
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