余光伟,毛新建,朱小杨.编辑通量图控制调强治疗计划的剂量冷热点[J].中华放射医学与防护杂志,2007,27(5):494-496.YU Guang-wei,MAO Xin-jian,ZHU Xiao-yang.Fluence map editing to control hot and cold spots of IMRT plan[J].Chin J Radiol Med Prot,2007,27(5):494-496
编辑通量图控制调强治疗计划的剂量冷热点
Fluence map editing to control hot and cold spots of IMRT plan
投稿时间:2006-07-24  
DOI:
中文关键词:  优化  编辑通量图  冷点  热点
英文关键词:Optimization  Fluence map editing  Cold spots  Hot spots
基金项目:
作者单位
余光伟 310009 杭州, 浙江大学医学院附属第二医院放射治疗科 
毛新建 湖州市中心医院介入放射治疗科 
朱小杨 310009 杭州, 浙江大学医学院附属第二医院放射治疗科 
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中文摘要:
      目的 研究手动编辑通量图控制调强治疗计划靶区内外剂量冷热点的优势。方法选择5例头颈肿瘤患者,回顾性比较二次优化和编辑通量图两种方法对控制靶区内外冷热点剂量分布的差别。结果 与第1次优化得到的调强治疗计划相比,第2次优化使靶区内外冷热点剂量分别增加0.5%、减少1.1%,而编辑通量图使靶区内外冷热点剂量分别增加1.0%、减少4.2%。结论 编辑通量图,特别是二次优化后剂量改善不明显的计划,对改善靶区内外冷热点剂量分布很有效。
英文摘要:
      Objective To investigate the advantage of manually editing intensity-modulated radiation therapy(IMRT) fluence maps to control hot and cold spots that the IMRT optimization cannot control. Methods Five patients with head-and-neck cancers were randomly enrolled, retrospective treatment planning study was performed to compare the efficiency between re-optimization and fluence maps editing to control dose hot and cold spots. Results Compared with the dose distribution of the first optimization, doses at hot(cold) spots decreased(increased) in the re-optimization plan with a median value of 1.1%(0.5%) and 4.2%(1.0%), respectively. Conclusions The fluence map editing technique on IMRT was proved effective to control hot and cold spots, especially when re-optimization cannot get a satisfactory result.
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