| 熊壮,王建华,余永强,等.同步辐射装置X线位相对比成像的初探[J].中华放射医学与防护杂志,2006,26(6):614-616.XIONG Zhuang,WANG Jian-hua,YU Yong-qiang,et al.Preliminary study on X-ray phase contrast imaging using synchrotron radiation facility[J].Chin J Radiol Med Prot,2006,26(6):614-616 |
| 同步辐射装置X线位相对比成像的初探 |
| Preliminary study on X-ray phase contrast imaging using synchrotron radiation facility |
| 投稿时间：2005-12-28 |
| DOI： |
| 中文关键词: 位相对比成像 X射线 同步辐射 |
| 英文关键词:Phase Contrast Imaging X-ray Synchrotron Radiation |
| 基金项目: |
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| 摘要点击次数: 3167 |
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| 中文摘要: |
| 目的 研究同步辐射光源X射线位相对比成像的方法,并观察其图像特点,分析其图像质量。方法 在北京同步辐射装置上对几种不同的生物样品进行X射线位相对比成像及传统的吸收对比成像,然后比较分析其图像。结果 几种生物样品均获得了满意的位相对比图像,其分辨率显著高于吸收对+比成像,清晰地显示出生物样品中约30～40μm的精细结构,并且能够显示吸收对比成像无法显示的一些组织结构。结论 利用同步辐射光源可进行X射线位相对比成像,与吸收对比成像相比,其图像质量有显著的提高。这种成像技术对于低吸收物体或吸收差异小的物体有着很高的应用价值。 |
| 英文摘要: |
| Objective To study the methodology of X-ray phase contrast imaging using synchrotron radiation, and evaluate the quality of phase contrast images. Methods Several experiments to obtain phase contrast images and absorption contrast images of various biological samples were conducted in Beijing Synchrotron Radiation Facility (BSRF), and then these images were interpreted to find out the difference between the two kinds of imaging methods. Results Satisfactory phase contrast images of these various samples were obtained, and the quality of these images was superior to that obtained with absorption contrast imaging. The phase contrast formation is based on the phenomenon of fresnel diffraction which transforms phase shifts into intensity variations upon a simple act of free-space propagation, so it requires highly coherent X-rays and appropriate distance between sample and detector. This method of imaging is very useful in imaging of low-absorption objects or objects with little absorption variation, and its resolution is far higher than that of the conventional X-ray imaging. The photographs obtained showed very fine inner microstructure of the biological samples, and the smallest microstructure to be distinguished is within 30-40 μm. There is no doubt that phase contrast imaging has a practical applicability in medicine. Moreover, it improves greatly the efficiency and the resolution of the existing X-ray diagnostic techniques. Conclusions X-ray phase contrast imaging can be performed with synchrotron radiation source and has some advantages over the conventional absorption contrast imaging. |
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