张力元,常韵芳,王彬彬,朱雅群,毛卫东,田野.医用射线防护喷剂防治皮肤黏膜放射性损伤的临床观察[J].中华放射医学与防护杂志,2006,26(6):597-599
医用射线防护喷剂防治皮肤黏膜放射性损伤的临床观察
Effect of protective spray against rays for medical use
投稿时间:2005-12-09  
DOI:
中文关键词:  急性皮肤放射性损伤  急性黏膜放射性损伤  超氧化物歧化酶  医用射线防护喷剂
英文关键词:Acute skin injury induced by iradiation  Acute mucous membrane injury induced by iradiation  Superoxide dismutase  Protective Spray against Rays for Medical Use
基金项目:装备预先研究资助项目(616010305)
作者单位
张力元 215004, 苏州大学附属第二医院放疗科 
常韵芳 215004, 苏州大学附属第二医院放疗科 
王彬彬 215004, 苏州大学附属第二医院放疗科 
朱雅群 215004, 苏州大学附属第二医院放疗科 
毛卫东 215004, 苏州大学附属第二医院放疗科 
田野 215004, 苏州大学附属第二医院放疗科 
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中文摘要:
      目的 探讨“医用射线防护喷剂”对皮肤和黏膜急性放射性损伤的临床价值。方法 70例首程放疗的头颈部恶性肿瘤患者,采用随机分组研究观察。观察组:用“医用射线防护喷剂”;对照组:不行任何治疗。结果 观察组皮肤黏膜的辐射损伤耐受剂量明显高于对照组(P<0.05);观察组中发生严重皮肤黏膜放射性损伤的概率低于对照组(P<0.05)。结论 “医用射线防护喷剂”对急性皮肤黏膜放射性损伤有明显的防护作用。
英文摘要:
      Objective To evaluate the effect of the Protective Spray against Rays for Medical Use on the acute mucocutaneous membrane injury induced by irradiation. Methods 70 patients who suffered from the malignant tumor of the head and neck were randomized into 2 groups after receiving radiotherapy for the first time. The treatment group was administered with the spray, while the control group was not. Results The radiation injury tolerance dose of mucocutaneous membrane in the treatment group was significantly higher than that in the control group (P<0.05), while the probability of the severe mucocutaneous membrane radiation injury in the treatment group is lower than that in the control group (P<0.05). Conclusions The Protective Spray against Rays for Medical Use has a protective effect on the acute mucocutaneous membrane injury induced by irradiation.
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