中华放射医学与防护杂志

刘建香,黄敏燕,阮健磊,等.哈尔滨事故受照者的生物剂量估算[J].中华放射医学与防护杂志,2006,26(5):460-462.LIU Jian-xiang,HUANG Min-yan,RUAN Jian-lei,et al.Biological dose estimation of victims in Harbin Accident of ¹⁹²Ir source[J].Chin J Radiol Med Prot,2006,26(5):460-462

哈尔滨事故受照者的生物剂量估算

Biological dose estimation of victims in Harbin Accident of ¹⁹²Ir source

投稿时间：2006-01-08

DOI：

中文关键词: 染色体畸变生物剂量估算 ¹⁹²Ir源事故

英文关键词:Chromosome aberration Biological dose assessment ¹⁹²Ir radiation accident

基金项目:科研院所社会公益研究专项重点项目(2003DIA6N009)

作者	单位	E-mail
刘建香	100088 北京, 中国疾病预防控制中心辐射防护与核安全医学所	suxu@nirp.cn
黄敏燕	100088 北京, 中国疾病预防控制中心辐射防护与核安全医学所
阮健磊	100088 北京, 中国疾病预防控制中心辐射防护与核安全医学所
苏旭	100088 北京, 中国疾病预防控制中心辐射防护与核安全医学所

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中文摘要:

目的对哈尔滨事故中的15例受检者进行生物剂量估算。方法采用加秋水仙素同步培养法培养受检者外周血淋巴细胞,分析染色体型畸变,用本实验室建立的剂量-效应曲线估算生物剂量。结果估算出6例受检者生物剂量,平均剂量范围为0.35～1.60Gy,结果与临床诊断相一致。另9例染色体畸变在正常范围。结论通过分析染色体畸变可以较准确地估算出生物剂量。

英文摘要:

Objective To estimate biological dose of victims in Harbin Accident of ¹⁹²Ir source. Methods Peripheral blood lymphocytes of the victims were cultured using conventional culture medium with colchicine added at the beginning. Unstable chromosome aberrations were scored and biological doses was estimated according to the dose_effect curves developed by our lab. Results The biological doses of six victims ranged from 0.35 to 1.60 Gy, which was consistent with the results of clinical diagnoses,while the frequencies of chromosome aberrations for another 9 victims were within the normal range. Conclusions Biological doses of victims in Harbin Accident were precisely assessed by analysis of chromosome aberrations.

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