| 陈超敏,唐木涛,周凌宏,吕庆文,王卓宇,陈光杰.调强放射治疗中剂量计算与射野参数优化研究[J].中华放射医学与防护杂志,2006,26(3):248-250 |
| 调强放射治疗中剂量计算与射野参数优化研究 |
| Study of dose calculation and beam parameters optimization with genetic algorithm in IMRT |
| 投稿时间：2005-07-11 |
| DOI： |
| 中文关键词: 调强放疗 剂量计算 卷积 遗传算法 参数优化 |
| 英文关键词:IMRT Dose calculation Convolution Genetic algorithm Parameters optimization |
| 基金项目:广东省科技计划资助项目(2003C32724);广州市科技攻关资助项目(2003Z3-E0411) |
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| 中文摘要: |
| 目的 研究调强放射治疗中剂量计算模型的建立与射野参数自动选择的实现方法。方法 用快速傅立叶变换建立三维光子卷积剂量计算模型,用基于剂量的目标函数作为遗传算法个体适应度的评价指标,用遗传算法实现射野权重的优化。结果 经过遗传算法100次迭代,能够得到适形度较高、剂量分布较均匀的剂量分布。结论 基于快速傅立叶变换的三维光子卷积剂量计算模型是一种较精确的模型;遗传算法是一种效率较高的IMRT射野参数优化方法。 |
| 英文摘要: |
| Objective To study the construction of dose calculation model and the method of automatic beam parameters selection in IMRT. Methods The three-dimension convolution dose calculation model of photon was constructed with the methods of Fast Fourier Transform. The objective function based on dose constrain was used to evaluate the fitness of individuals. The beam weights were optimized with genetic algorithm. Results After 100 iterative analyses, the treatment planning system produced highly conformal and homogeneous dose distributions. Conclusion the three-dimension convolution dose calculation model of photon gave more accurate results than the conventional models; genetic algorithm is valid and efficient in IMRT beam parameters optimization. |
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