| 金普乐,王敏,丁翠敏.气道内悬挂125I粒子治疗中心性肺癌引起的气道狭窄[J].中华放射医学与防护杂志,2006,26(1):74-76.JIN Pu-le,WANG Min,DING Cui-min.Malignent airway stricture treated by endobronchial brachytherapy with125I suspended in airway[J].Chin J Radiol Med Prot,2006,26(1):74-76 |
| 气道内悬挂125I粒子治疗中心性肺癌引起的气道狭窄 |
| Malignent airway stricture treated by endobronchial brachytherapy with125I suspended in airway |
| 投稿时间：2005-11-28 |
| DOI： |
| 中文关键词: 125I 腔内放疗 肺癌 |
| 英文关键词:125I Endobronchial brachytherapy Lung cancer |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨经环甲膜穿刺,气道内悬挂125I粒子对肺癌引起的气道狭窄和肺不张进行腔内近距离放疗的效果。方法中心型肺癌21例,在纤维支气管镜或X线引导下,经环甲膜穿刺、置管、气道内悬挂125I放射性微粒子,对肺癌进行持续近距离放疗。观察时间为3个月。结果 本组21例患者中,气道狭窄完全缓解5例,部分缓解10例,无变化4例,恶化2例,有效率(完全缓解+部分缓解)为15例。并发颈部瘘口炎性肉芽组织增生、喉部不适、导管刺激性咳嗽各3例,WBC下降低于正常2例,导丝在颈部折断1例。结论 经环甲膜穿刺、置管、气道内悬挂125I粒子治疗肺癌引起气道狭窄和肺不张是有效和安全的。 |
| 英文摘要: |
| Objective To evaluate the efficacy and safety of endobronchial brachytherapy to malignent airway stricture with125I implanted via cricothyroid membrane puncture and suspended in airway.Methods A total of 21 patients with central lung cancer had undergone endobronchial brathytherapy with125I implanted via cricothyroid membrane puncture and suspended in airway which guided by X-ray or fiberoptic bronchoscopy.The treating time was for three months.Results In 21 cases,CR、PR、AC、and PD were 5(24%)、10(48%)、4(19%) and 2(9%)respectively,CR+PR was 15(72%).The complications such as inflammatory granuloma in neck,laryngeal malaise,irritating cough were just the same 3 patients(14%),hypoleuko-cytosis and broken guidewire in neck were 2(9%)and 1(5%)respectively.Conclusion Endobronchial brachytherapy with125I implanted via cricothyroid membrane puncture and suspended in airway for lung cancer is quite effective and safe. |
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