诸洪达,张永保,王松君,王耐芬,陈如松,刘庆芬,王珂,常平,刘虎生,欧阳荔,刘雅琼.52例中国人主要器官、组织中37种元素的负荷量研究[J].中华放射医学与防护杂志,2004,24(4):304-307
52例中国人主要器官、组织中37种元素的负荷量研究
Burdens of 37 elements in main organs and tissues for 52 cases of Chinese man
投稿时间:2003-06-25  
DOI:
中文关键词:  中国人  元素  器官组织  浓度  负荷量
英文关键词:Chinese man  Element  Organ and tissue  Concentration  Burden
基金项目:国家自然科学基金资助项目(39970234)
作者单位
诸洪达 Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, China 
张永保  
王松君  
王耐芬  
陈如松  
刘庆芬 Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, China 
王珂  
常平  
刘虎生  
欧阳荔  
刘雅琼  
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中文摘要:
      目的 估算37种元素在中国成年男子主要器官、组织和全身的负荷量。方法 在我国4个不同膳食类型地区补充采集21例急死正常尸体肌肉、肋骨、肝、肾、肺、甲状腺、心、胃、脾和小肠样品,连同过去31例尸体所采集样品对37种元素的测定浓度,按中国参考人器官、组织重量参考值估算了相应器官、组织和全身的负荷量。结果 获得了我国成年男子10种器官、组织中37种元素器官、组织和全身的负荷量。结论 首次获得的这些结果为确定中国人器官、组织所测元素负荷量背景值和中国参考人相应负荷量参考值及生物动力学模型参数提供较前更为系统和有代表性的依据。
英文摘要:
      Objective To estimate elemental burdens in main organs, tissues and the whole body of a Chinese adult man. Methods Muscle, rib, liver, kidney, lung, thyroid, heart, stomach, spleen and small intestine samples were obtained in autopsy from 21 supplemental subjects died suddenly, who had been healthy and normal before death and lived in 4 areas with different dietary types in China. Based on determined concentrations of 37 elements in these samples together with those in samples of 31 subjects collected in the past, the organ or tissue and body burdens were estimated by using relevant organ, tissue weights for Chinese Reference Man. Results The data for burdens of 37 elements in 10 kinds of organs or tissues and the whole body for these Chinese adult men were obtained. Conclusion Besides improving representative property of the formerly reported results for I in thyroid and 33 elements in other 5 kinds of organs or tissues, this research obtained the burden data of these elements in heart, stomach, spleen, small intestine and Be, Cl, S, I in these 10 kinds of organs or tissues (except I in thyroid) for the first time in China. These results provide more systematic and representative basis for developing background values of determined elements, both reference values of related burdens for Chinese Reference Man and parameters of bio-kinetic models than before.
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