罗素明,李开宝,何志坚,等.热释光剂量计核查非参考条件下放射治疗剂量学参数的研究[J].中华放射医学与防护杂志,2004,24(2):95-98.LUO Su-ming,LI Kai-bao,HE Zhi-jian,et al.Development of TLD-based quality audit for radiotherapy dosimetry in non-reference condition[J].Chin J Radiol Med Prot,2004,24(2):95-98
热释光剂量计核查非参考条件下放射治疗剂量学参数的研究
Development of TLD-based quality audit for radiotherapy dosimetry in non-reference condition
投稿时间:2003-05-18  
DOI:
中文关键词:  TLD核查  放疗剂量  非参考条件
英文关键词:TLD quality audit  Radiotherapy dosimetry  Non-reference condition
基金项目:IAEA资助项目(11916RO)
作者单位
罗素明 100088 北京, 中国疾病预防控制中心辐射防护与核安全医学所 
李开宝 100088 北京, 中国疾病预防控制中心辐射防护与核安全医学所 
何志坚 100088 北京, 中国疾病预防控制中心辐射防护与核安全医学所 
邱杰 北京协和医院 
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中文摘要:
      目的 用TLD核查在非参考条件下,光子束轴向和电子束轴向最大剂量点处,剂量随深度、距离、照射野和45°楔形板等变化的临床剂量学参数研究。方法 在非参考条件下,TLD经60Coγ射线束,6MV和15MV高能X射线束,9MeV和16MeV高能电子束测量并估算剂量。结果 经TLD核查,对不同射线质在不同深度,用不同指型电离室测量,除了TLD在水中深度20cm处应做支架减弱效应减弱校正外,其余临床剂量学参数核查结果表明,TLD测量结果与指型电离室测量的参考剂量结果相对误差值均在±49%(IAEA允许误差±5%)以内;对高能电子线束,用平行板电离室测量,绝大多数TLD相对误差值超过±5%。结论 用TLD核查非参考条件下,放射治疗临床剂量学参数方便,准确可靠,经在医院做可行性验证,IAEA推荐的两种TLD照射支架(一种用于光子束,另一种用于电子束)具有可行性;对高能电子线束用平行板电离室测量,TLD验证方法待做进一步研究。
英文摘要:
      Objective To study on quality audits of clinic dosimetry parameters with TLDs for photon dose on beam axis and the maxima depth doses of high energy electron beams, testing the dose variation with depth, distance, field size and 45° wedge in non-reference conditions. Methods TLDs were irradiated in 60Coγ-ray, 6 MV and 15 MV high energy X ray and 9 MeV and 16 MeV high energy electron beams, then TLD doses were evaluated. Results All the TLD results are in agreement within ±4. 9% (IAEA acceptable deviation ±5%) with the reference dose measured with cylindrical chambers except for TLD results at 20 cm depth which should be corrected for the decrease of TLD response due to partial holder attenuation of the beams. But most of the TLD results for high energy electron beams are different from the reference doses measured by plane parallel chamber with the deviation of larger than ±5%. Conclusion It is convenient and accurate to use TLD method for quality audits of clinic dosimetry parameters in radiotherapy. Two kinds of IAEA TLD holders (one for photon beam, another for electron beam) are feasible for use in TLD audits. The reasons causing deviation between the TLD results and dose results measured by plane parallel chamber should further be studied.
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