| 韦鹏翔,艾泉山,陈旭,夏吉勇,陈炳桓.癫痫的X刀治疗[J].中华放射医学与防护杂志,2004,24(1):57-59 |
| 癫痫的X刀治疗 |
| X knife treatment of epilepsy |
| 投稿时间：2003-07-19 |
| DOI： |
| 中文关键词: 继发性癫痫 原发性颞叶癫痫 X刀 治疗 |
| 英文关键词:Secondary epilepsy Idiopathic temporal lobe epilepsy X knife Treatment |
| 基金项目:解放军沈阳军区科研课题(1999);吉林省卫生厅科研课题(1998011) |
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| 中文摘要: |
| 目的 探讨X刀治疗继发性癫痫(SEp)和原发性颞叶癫痫(ITLEp)的方法。方法 使用24hEEG、CT、MRI对继发性癫痫灶定位,应用X刀损毁致痫灶治疗SEp40例;毁损剂量20～30Gy。应用X刀毁损杏仁核治疗ITLEp病人30例;毁损剂量140Gy;准直仪7～10mm;采用140Gy一次和分两次毁损治疗(每次间隔24h)。结果 40例SEp病人和30例ITLEp病人X刀治疗后4～24个月随访:50例病人癫痫发作完全停止(SEp32例,ITLEp18例);20例病人发作减少50%以上;无并发症发生。结论 应用X刀毁损SEp致痫灶及杏仁核,可安全有效地治疗SEp和ITLEp。 |
| 英文摘要: |
| Objective To investigate the curative effect of X knife treatment method for secondary epilepsy (SEp) and idiopathic temporal lobe epilepsy (ITLEp). Methods The 24-hour EEG,CT,MRI were used for locating the epileptogenic lesion of SEp.Forty patients of SEp were treated to destroy epileptogenic lesion by X knife with dose,20-30 Gy.Thirty patients of ITLEp were treated with X knife for amygdalectomy at 140 Gy and collimator 7-10 mm.The 140 Gy were given either by single full dose or 2-time fractionated treatment (Q.24.h). Results By 4-24 month follow-up of all these patients it was showed that seizures were alleviated completly in 50 patients (SEp 32 cases,ITLEp 18 cases),alleviated over 50% in 20 patients (SEp 8 cases,ITLEp 12 cases).No complications were observed. Conclusion X knife treatment of SEp is a useful and safe method to destroy epileptogenic lesion in patients with SEp and to perform amygdalectomy in patients with ITLEp.This methods is thus proved to be effective for such patients. |
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