张卫,王继先,赵永成,李本孝,樊体强.我国医用诊断X射线工作者高血压危险因素研究[J].中华放射医学与防护杂志,2002,22(4):246-249 |
我国医用诊断X射线工作者高血压危险因素研究 |
Risk factors of hypertension among medical diagnostic X-ray workers in China |
投稿时间:2001-06-15 |
DOI: |
中文关键词: 医用诊断X射线工作者 高血压 电离辐射 危险因素 病例对照研究 |
英文关键词:Medical diagnostic X-ray workder Essential hypertension onizing radiation Risk factors Case-control study |
基金项目:日本体质研究会基金资助项目 |
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中文摘要: |
目的 研究我国医用诊断X射线工作者中高血压病发病的危险因素,探讨长期职业受照与高血压发病之间的关系。方法 采用整群随机抽样的方法,在全国范围内选取288对1:2配比的医用诊断X射线工作者高血压患者及相应对照,问卷调查各种可能的危险因素,归一化工作量法估算累积受照剂量,SAS软件COX比例风险模型进行单因素及多因素条件Logistic回归分析。结果 超重(OR=3.087,P=0.001)、高血压家族史(OR=3.140,P=0.001)、担心从事放射工作有害健康(OR=1.798,P=0.010)是我国X射线工作者高血压3个主要危险因素;将性别、参加工作年代分层后,男性、早期参加放射工作者中较大剂量受照同高血压呈正相关(OR=5.672,P=0.022)。结论 家族史、超重是&射线工作者高血压主要危险因素,职业紧张在&射线工作者高血压中发挥一定的作用,较大剂量受照可能与高血压有关。 |
英文摘要: |
Objective To investigate the risk factors of essential hypertension in medical diagnostic X-ray workers in China, especially for the relationship between essential hypertension and occupational irradiation. Methods A 1:2 matched case-control study was carried out.The study subjects consisted of 288 pairs of matched cases and controls coming from different hospitals in China.Information about occupational and non-occupational risk factors were obtained through questionnaire.Individual doses were estimated by normalized workload method.Conditional Logistic regression method was applied to data analysis with SAS6.12 software. Results Variables such as overweight (OR=3.087, P =0.001), family history of hypertension (OR=3.140, P =0.001), worring about X-ray work as a health-damaging occupation (OR=1 798, P =0.010) were three main risk factors in the ungrouped data.Dividing the study subjects into different subgroups according to sex and calendar period of entry, the highest level of accumulated dose (>300 mGy) as a risk factor had statistically reached significant level in the male X-ray workers of the earlier period of entry (OR=5.672, P =0.22). Conclusion For medical diagnostic X-ray workers, overweight, family history of hypertension and occupational stress are the main risk factors of essential hypertension.For those accumulated doses over 300 mGy, indicating ionizing radiation may be a potential risk factor.As there is no reasonable biological mechanism to explain these findings, further studies are needed. |
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