| 王继先,李本孝,赵永成,高智伟,徐钧,张景源,青山乔.中国医用诊断X射线工作者1950～1995年恶性肿瘤危险分析[J].中华放射医学与防护杂志,2002,22(4):234-238 |
| 中国医用诊断X射线工作者1950～1995年恶性肿瘤危险分析 |
| Risk analysis of malignant tumor among medical diagnostic X-ray workers in China,1950-1995 |
| 投稿时间：2001-10-30 |
| DOI： |
| 中文关键词: 医用诊断X射线工作者 恶性肿瘤 辐射致癌 |
| 英文关键词:Medical diagnostic X-ray worker Malignant tumor Radiocarcinogenesis |
| 基金项目:日本体质研究会基金资助项目 |
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| 全文下载次数: 1958 |
| 中文摘要: |
| 目的 提供职业照射诱发人类恶性肿瘤的证据和评价其危害。方法 用O/E程序分析了我国24省、直辖市、自治区1950～1980年间在职的27011名医用诊断X射线工作者和25782名其他科医务工作人员1950～1995年间的恶性肿瘤发病资料。结果 X射线工作者的恶性肿瘤发病率明显高于对照医务人员,相对危险(RR)为12,95%可信限(CI)为1.1～1.3.发病率明显增加的肿瘤是白血病、皮肤癌、女性乳腺癌、肺癌、肝癌、膀胱癌和食管癌;RR分别为:22、41、13、12、12、18和2.7.甲状腺癌的发病率也见增高,RR=1.6,95%(CI)为0.9～2.6。结论 X射线工作者白血病、皮肤癌、女性乳腺癌,可能还有甲状腺癌相对危险的增高与职业&射线的照射有关,当累积剂量达到一定水平时,这些肿瘤的相对危险明显增高。 |
| 英文摘要: |
| Objective To provide evidence of human malignant tumors induced by occupational exposure to ionizing radiation and to assess the resultant cancer risk. Methods Cancer incidence (1950-1995) among 27 011 medical X-ray workers was compared by means of O/E system with that of 25 782 other medical specialists employed between 1950 and 1980 in China. Results Significant cancer risk was seen among medical X-ray workers (RR=1.2, 95% CI:1.1-1.3).Significantly elevated risks were found for leukemia and cancer of skin, female breast, lung, liver, bladder and esophangus, the RRs were 2 2, 4 1, 1 3, 1 2, 1 2, 1 8 and 2 7, respectively.The RR of thyroid cancer also elevated but was not significant (RR=1.6, 95% CI:0. 9-2.6).The patterns of risk associated with number of years engaging in X-ray work, age, the calendar year of initial employment, and cumulative dose, suggesting that the excesses of leukemia, skin cancer, female breast cancer, and possibly thyroid cancer, were related to occupational exposure to X-rays. Conclusion These findings suggest that a significant cancer risk can be associated with occupational exposure to ionizing radiation when the cumulative dose reaches a certain level. |
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