李智华.乳腺癌切线照射中肺受照体积的量化分析[J].中华放射医学与防护杂志,2002,22(1):58..Risk factors of coronary heart disease among medical diagnostic X-ray workers[J].Chin J Radiol Med Prot,2002,22(1):58 |
乳腺癌切线照射中肺受照体积的量化分析 |
Risk factors of coronary heart disease among medical diagnostic X-ray workers |
投稿时间:2001-02-25 |
DOI: |
中文关键词: 医用诊断X射线工作者 冠心病 危险因素 病例对照研究 电离辐射 |
英文关键词:Medical diagnostic X-ray worker Coronary heart disease Risk factors Case-control study Ionizing Radiation |
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中文摘要: |
早期乳腺癌的术后放疗采用乳腺定位板、等中心(SAD)摆位技术、非对称半野照射以及三维治疗计划系统的优化等技术对早期乳腺癌行术后切线放疗已成定式, 特别是非对称半野照射技术已被某些放疗中心所采用, 它能有效地降低肺部受照射剂量, 但是其对肺部剂量的改善程度尚少见报道1,2.笔者通过比较三维治疗计划系统给出的体积剂量直方图, 对对称野和非对称半野照射在乳腺癌切线照射时肺受照射体积进行量化比较和分析。一、材料和方法1体位及射野:患者仰卧在平床上, 手臂上举并握住乳腺定位棒。切线照射野的宽度应以包括全部乳腺组织及胸廓并尽量减少所照的肺组织为原则。 |
英文摘要: |
Objective To investigate risk factors of coronary heart disease (CHD) in medical diagnostic X-ray workers in China, especially the relationship of CHD with occupational irradiation. Methods A 1∶2 matched case-control study was carried out. The study subjects consisted of 112 pair-matched cases and controls coming from different hospitals in China. Information about occupational and non-occupational risk factors obtained by interviewing every subjects personally. Individual doses were estimated by normalized work load method. SAS 6.12 software conditional Logistic regression method was applied to data analysis. Results Variables such as family history of CHD (OR= 17.298, P=0.0001), history of hypertension (OR=6.172, P=0.0003), overweight (OR=2.679, P=0.0150), physical exercises (OR=0.421, P=0.0333), diabetes (OR= 7.823, P=0.0200), radiation protection condition(OR=3.992, P=0.0027), and accumulated radiation dose(OR=1.612, P=0.0454) were included in the last model. Conclusions For the medical diagnostic X-ray workers, family history of coronary heart disease , history of hypertension, diabetes, etc. are the main risk factors of CHD, and occupational exposure may be a potential risk factor. As for the mechanism, further studies are needed. ; |
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