孙全富,秋叶澄伯,陶祖范,等.阳江天然放射性高本底辐射慢性照射与实体癌超额危险[J].中华放射医学与防护杂志,2002,22(1):51-54.SUN Quanfu,AKIBA Suminori,TAO Zufan,et al.Excess relative risk for solid cancer mortality during prolonged exposure to high-background natural radiation in Yangjiang area of China[J].Chin J Radiol Med Prot,2002,22(1):51-54 |
阳江天然放射性高本底辐射慢性照射与实体癌超额危险 |
Excess relative risk for solid cancer mortality during prolonged exposure to high-background natural radiation in Yangjiang area of China |
投稿时间:2001-03-30 |
DOI: |
中文关键词: 群组研究 癌症 小剂量 剂量估算 超额危险 |
英文关键词:Cohort study Cancer Low-dose Dose estimation Excess risk |
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中文摘要: |
目的 估算阳江高本底辐射慢性照射可能导致的实体癌超额相对危险。方法 基于自然村室内、外环境剂量和性别年龄别居留因子, 估算研究群组每一个成员的累积剂量。假定剂量与癌症危险间存在线性关系, 利用1979~1995年的癌症死亡率资料, 按照Poisson模型计算超额相对危险。结果 全部实体癌超额相对危险(ERR)为-0.11(95%CI,-0.67,0.69)Sv.肝癌、鼻咽癌、肺癌和胃癌等前4位癌症的ERR(95%CI)Sv分别为-0.99(-1.60,0.10),0.10(-1.21,3.28),-0.68(-1.58,1.66)和-0.27(-1.37,2.69).结论 未发现实体癌超额相对危险与剂量有关。 |
英文摘要: |
Objective To estimate the excess relative risk for solid cancer associated with chronically exposure to high-background natural radiation in Yangjiang area of China. Methods Based on hamlet-specific environmental doses and sex-and age-specific occupancy factors,we calculated cumulative doses for each cohort member.Assuming a linear dose response relationship and using cancer mortality data for the period 1979-1995 and Poisson model,we estimated the excess relative risk(EER)for solid cancer. Results The ERR per Sv of all solid cancer is estimated to be -0.11(95% CI,-0.67,0.69 to 95%).The corresponding figures for cancers of liver,nasopharynx,lungs and stomach are -0.99(-1.60,0.10),0.10(-1.21,3.28),-0.68(-1.58,1.66) and -0.27(-1.37,2.69)respectively. Conclusion The association between ERR of solid cancer and dose can not be found. |
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