范士怀,贺方学,葛来增,等.自体血照射回输在鼻咽癌放射治疗中的作用[J].中华放射医学与防护杂志,2002,22(1):42-43.,et al.Clinical studies of effect of Jinshi Granule on reducing the toxic radiotherapy reaction in nasopharyngeal carcinoma[J].Chin J Radiol Med Prot,2002,22(1):42-43
自体血照射回输在鼻咽癌放射治疗中的作用
Clinical studies of effect of Jinshi Granule on reducing the toxic radiotherapy reaction in nasopharyngeal carcinoma
投稿时间:2001-04-24  
DOI:
中文关键词:  金石颗粒剂  鼻咽癌  放射反应
英文关键词:Jinshi Granule  Nasopharyngeal carcinoma  Toxic reaction of radiotherapy  
基金项目:山东省科委重点基金资助项目(951197502)
作者单位
范士怀 276001 山东, 临沂市肿瘤医院 
贺方学 276001 山东, 临沂市肿瘤医院 
葛来增 276001 山东, 临沂市肿瘤医院 
申源峰 276001 山东, 临沂市肿瘤医院 
吕相坤 276001 山东, 临沂市肿瘤医院 
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中文摘要:
      鼻咽癌放射治疗中, 多见发生急性放射性口咽粘膜炎、白细胞降低及免疫机能下降;合并化疗时更为严重, 如何进行有效地防治, 一直是临床上重要的研究课题。我们在行自体血照射回输提高机体抗辐射能力的系列研究中13,重点观察了自体血照射回输在鼻咽癌放射治疗中的作用, 报道如下。一、材料和方法1临床资料:自1996年5月2日~1999年5月2日, 收治的107例鼻咽癌随机分研究组55例, 对照组52例。
英文摘要:
      Objective To study the effects of Jinshi Granule (JSG) on decreasing the toxic reaction of radiotherapy in nasopharyngeal carcinoma (NPC) patients in order to search for an effective method and medicines. Methods Altogether 90 patients with NPC treated by radical radiotherapy were divided into three groups at random. Each group consisted of 30 patients who all received radiotherapy.Patients of the 1st treatment group were treated by JSG, the 2nd treatment group by Biyan Qingdu Ji(BQJ), and the control group by placebo. Results ①In JSG group, the effective rate, the rate of completing radiotherapy, the enhancing and stabilization rate of quality of life were 93.33%, 96.67%, and 90.00%, respectively, which were all higher than those in other groups(P<0.05, P<0.01).②The degree of the toxic reaction syndromes in the JSG group was lower than that in other two groups and the stabilization of peripheral hemogram was much better (P<0.05, P<0.01). Conclusion These data show that JSG has significant effects on reducing the toxic reaction of radiotherapy to NPC and combining it with radiotherapy is an effective method in treating NPC.
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