| 白玉书,黄绮龙,关树荣,等.快中子对X和γ射线诱发淋巴细胞微核效应的比较研究[J].中华放射医学与防护杂志,1998,18(4):259-262.Bai Yushu,Huang Qilong,Guan Shurong,et al.A comparative study on micronuclei induced by fast neutrons versus X and 60Co γ rays in human peripheral blood lymphocytes[J].Chin J Radiol Med Prot,1998,18(4):259-262 |
| 快中子对X和γ射线诱发淋巴细胞微核效应的比较研究 |
| A comparative study on micronuclei induced by fast neutrons versus X and 60Co γ rays in human peripheral blood lymphocytes |
| 投稿时间：1997-10-20 修订日期：1998-01-19 |
| DOI： |
| 中文关键词: 快中子 X射线 60Co γ射线 相对生物效能 |
| 英文关键词:Fast neutrons X-rays 60Co γ rays Relative biological effectiveness |
| 基金项目:卫生部科学研究基金 |
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| 中文摘要: |
| 目的 比较2.14MeV中子对180kVX射线和60Co γ射线诱发微核的效应。方法 用不同剂量快中子、X射线和γ射线照射离体人血, 观察双核淋巴细胞微核, 求出快中子对X和γ射线的相对生物效能。结果 2.14MeV中子对180kVX射线和60Co γ射线的相对生物效能在1～3Gy范围内, 随剂量增加而降低, 平均分别为3.88和4.50.结论 2.14MeV中子具有较高的生物效应 |
| 英文摘要: |
| Objective To compare the effectiveness of 2.14MeV neutrons versus 180kV X-rays and 60Co γ rays in producing micronuclei in human lymphocytes.Methods Heparinized whole blood samples were exposed to fast neutrons, X-rays and 60Co γ rays, respectively.Micronuclei in binuclear lymphocytes(CB method)were scored.Relative biological effectiveness (RBE) values were derived.Results RBE values of 2.14MeV neutrons ranging from 1 to 3 Gy decreased with increasing dose.They averaged 3.88(Dx/Dn) and 4.50(Dγ/Dn), respectively.Conclusion 2.14MeV neutrons have higher biological effectiveness in inducing micronuclei. |
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