| 王继先,李本孝,高智伟,徐钧,张景源.我国医用诊断X射线工作者1950年～1990年间恶性肿瘤危险分析[J].中华放射医学与防护杂志,1998,18(2):113-117 |
| 我国医用诊断X射线工作者1950年～1990年间恶性肿瘤危险分析 |
| Risk analysis of malignant tumors among Chinese medical diagnostic X-ray workers in 1950 1990 |
| 投稿时间：1997-03-17 修订日期：1997-04-14 |
| DOI： |
| 中文关键词: 医用X射线工作者 辐射致癌 恶性肿瘤 |
| 英文关键词:Medical X-ray Radiologists Radiation carcinogenesis |
| 基金项目:日本体质研究基金会部分资助 |
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| 中文摘要: |
| 目的 提供小剂量慢性照射诱发人类恶性肿瘤的证据和有关规律。方法 用O/E程序分析了我国24个省、直辖市、自治区27011名医用诊断X射线工作者和25782名其他科医务人员1950～1990年间恶性肿瘤发病资料。结果 X射线工作者的恶性肿瘤发病率显着高于对照医务人员(RR=1.1,95%可信限为1.0～1.2).发病率明显增加的恶性肿瘤是白血病、皮肤癌、妇女乳腺癌、肝癌和食管癌, 相对危险分别为：2.3,5.0,1.6,1.3和4.4.白血病危险的增高主要见于1970年前开始X射线工作和开始放射工作时年轻者。结论 从X射线工作者恶性肿瘤的相对危险与工龄、参加X射线工作时年龄和时期分析表明, X射线工作者的白血病、皮肤癌和妇女乳腺癌发病率的增加与职业X射线照射有关。 |
| 英文摘要: |
| Objective To provide evidence and related patterns of formation of human malignant tumors induced by prolonged exposure to low level ionizing radiation.Methods The cancer incidence (1950 1990) among 27011 medical diagnostic X-ray workers was compared with that among 25782 other medical specialists employed between 1950 and 1980 in China by means of O/E system.Results A significantly elevated risk of cancer was seen among diagnostic X-ray workers(RR=1.1,95%CI=1.0- 1.2, P <0.05).Significantly elevated risks were seen for leukemia and cancers of skin,female breast,liver and esophagus,the RR being 2.3.5 .0,1.6.1 .3 and 4.4,respectively.The RR for leukemia was higher for X-ray workers who began employment before 1970 and also for those who were young when employment began.Conclusion The patterns of risk associated with length of service and with age and calendar year of initial employment suggest that the excesses of leukemia,skin cancer and female breast cancer were due to occupational exposure to X-rays. |
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