李嘉,菅崎弘之,杨宇华,三根真理子,查永如,岸川正大,孙全富,中根允文,邹剑明,朝长万左男,陶祖范.阳江天然放射性高本底地区老年痴呆患病率的调查[J].中华放射医学与防护杂志,1997,17(4):271-275
阳江天然放射性高本底地区老年痴呆患病率的调查
A survey of senile dementia in the high background radiation areas in Yangjiang, China
投稿时间:1996-05-28  修订日期:1996-09-23
DOI:
中文关键词:  小剂量  低剂量率  电离辐射  老年痴呆  患病率
英文关键词:Prevalence rate  Senile dementia  Low dose  Low dose rate  Ionizing radiation 
基金项目:日中医学协会的资助
作者单位
李嘉 100088 北京, 卫生部工业卫生实验所 
菅崎弘之 日本, 长崎大学医学部 
杨宇华 广东省职业病防治院 
三根真理子 日本, 长崎大学医学部 
查永如 广东省职业病防治院 
岸川正大 日本, 长崎大学医学部 
孙全富 100088 北京, 卫生部工业卫生实验所 
中根允文 日本, 长崎大学医学部 
邹剑明 广东省职业病防治院 
朝长万左男 日本, 长崎大学医学部 
陶祖范 100088 北京, 卫生部工业卫生实验所 
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中文摘要:
      目的 研究长期小剂量低剂量率电离辐射照射对老年痴呆病的影响, 为研究小剂量电离辐射对中枢神经系统影响及老年痴呆的病因学提供对人类的直接观察资料。方法 在中国广东省阳江高本底地区进行老年痴呆病患病率的现况调查, 筛选阶段应用长谷川智力量表, 确诊阶段应用老人健康状况调查专门用表。以美国精神疾病诊断和统计手册修订第3版(DSMⅢ-R)为诊断标准。结果 共调查65岁及以上老年人1018人, 其中高本底地区513人, 对照地区505人, 按DSMⅢ-R为诊断标准, 共确诊老年痴呆病61例, 其中高本底地区31例, 对照地区30例。总患病率为5.99%,高本底地区为6.04%,对照地区为5.94%.结论 该高本底地区和对照地区老年痴呆患病率差异无显着性
英文摘要:
      bjective To evaluate the effects of long-term low dose and low dose-rate ionizing radiation exposure on the prevalence rate of senile dementia,further assess the effects of low dose radiation exposure on central nervous system and study the pathogen of senile dementia,and provide direct observational data of human beings. Methods A cross-sectional study of the prevalence of senile dementia was carried out in high background radiation areas in Yangjiang,Guangdong Province,China.The survey was conducted in two stages.For the initial screening,Hasegawa Dementia Scale (HDS) was used for all subjects.In the second stage, the stage of diagnosis,special questionnaires of healthy state of old people were used. The final diagnoses were made according to the third revised edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM Ⅲ-R) of American Psychiatric Association. Results 1018 inhabitants aged 65 years and over,including 513 persons in HBRA and 505 in CA were oberved.According to DSMⅢ-R,61 cases (31 cases in HBRA and 30 cases in CA)of senile dementia were diagnosed.The prevalence rates of senile dementia are 6.04% in HBRA and 5.94% in CA,the total prevalence rate being 5.99%. Conclusion No significant statistical difference in the prevalence rate of senile dementia between the two areas was found,suggesting that the prevalence rate of senile dementia in these areas is not associated with the high background radiation exposure.
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