朱寿彭,夏芬,杨卫东.信号核素134Cs诱发体细胞和生殖细胞畸变效应比较研究[J].中华放射医学与防护杂志,1997,17(4):239-242.Zhu Shoupeng,Xia Fen,Yang Weidong.Comparison of chromosome aberration yields induced by signal radionuclide 134Cs in somatic and germ cells[J].Chin J Radiol Med Prot,1997,17(4):239-242
信号核素134Cs诱发体细胞和生殖细胞畸变效应比较研究
Comparison of chromosome aberration yields induced by signal radionuclide 134Cs in somatic and germ cells
投稿时间:1996-05-03  修订日期:1996-07-05
DOI:
中文关键词:  信号核素  134Cs  体细胞  生殖细胞  畸变产额
英文关键词:Radionuclide  Cesium-134  Somatic cells  Germ cells  Chromosome aberrations
基金项目:国家自然科学基金
作者单位
朱寿彭 215007 江苏, 苏州医学院放射医学系 
夏芬 215007 江苏, 苏州医学院放射医学系 
杨卫东 215007 江苏, 苏州医学院放射医学系 
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中文摘要:
      目的134Cs诱发体细胞和生殖细胞的畸变效应进行了比较研究。方法 观察内污染不同放射性活度134Cs时诱发同体骨髓细胞和精原细胞染色体畸变的量效关系, 以及同一放射性活度134Cs作用不同时间诱发上述两种细胞的染色体畸变产额。结果 研究发现, 134Cs内照射诱发的骨髓细胞染色体畸变产额显着高于精原细胞, 而其诱发的染色体畸变类型均以染色单体型畸变为主。结论 由不同放射性活度134Cs所诱发的染色体畸变产额而言, 骨髓细胞要比精原细胞高出1.5~5倍。
英文摘要:
      bjective To compare the aberration inducing effect of 134Cs in somatic and germ cells. Method Studying dose response relationship for 134Cs at different radioactivities inducing chromosome aberrations in somatic and germ cells,as well as 134Cs in the same radioactivity inducing aberration yields after different time intervals. Results It was demonstrated that the chromosome aberration yields induced by 134Cs in bone marrow cells were significantly higher than those in spermatogonia.Most of chromosome aberrations in bone marrow cells and spermatogonia were similar in chromatid type. Conclusion The results suggest that the dose-response relationship of aberration yields in bone marrow cells induced by 134Cs at different radioactivities is 1.5-5 times higher than that in spermatogonia.
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