| 金璀珍,刘秀林,张泽云.一例192Ir源辐射事故病人受照生物剂量的估算[J].中华放射医学与防护杂志,1997,17(1):34-36 |
| 一例192Ir源辐射事故病人受照生物剂量的估算 |
| Cytogenetic dosimetry for a victim accidentally exposed to 192 Ir gamma rays. |
| 投稿时间：1996-05-03 修订日期：1996-09-04 |
| DOI： |
| 中文关键词: 生物剂量 染色体畸变 |
| 英文关键词:Biological dosimetry Chromosome aberrations |
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| 中文摘要: |
| 目的 用染色体畸变分析方法对一例192Ir源辐射事故病人进行生物剂量估计。方法 照后72小时取血培养,分析M1细胞双着丝粒加环畸变频率作为生物剂量估算依据,并于照后31天,66天追踪观察。同时用双+环畸变在细胞间的泊松分布统计检验,以示照射的均匀性。结果 根据照后72小时双+环频率估算个体辐射剂量为2.9Gy,这一剂量与物理方法测定的剂量比较接近,与临床放射损伤的诊断也是一致的。事故后31,66天又取血培养,分析双+环畸变数与照后72小时差别不大。同时用双+环畸变数在细胞间的泊松分布统计检验,证实偏离泊松分布。结论 这是一例高度不均匀照射病例。 |
| 英文摘要: |
| Objective Cytogenetic dosimetry was performed for a victim who was over exposed to 192Ir gamma rays.Methods The individual dose was estimated by the yields of dicentrics plus rings.Results Based on the cytogenetic findings,the equivalent whole body dose was estimated to be 2.9Gy.This dose was in good agreement with the mean dose calculated from physical measurement and conformable to the clinical diagnosis.Follow-up studies of chromosome aberrations were carried out 31st and 66th days after the accident.It was shown that the yields of dic+r were reasonably constant.A non Poisson distribution of dic+r and the presence of a few multi-aberrant cells were consistent with the non uniform exposure.Conclusion This was a highly inhomogeneously irradiated case. |
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