赵慧云,李五岭,饶用清,等.估算含氚细胞核吸收剂量不同模式的相互比较[J].中华放射医学与防护杂志,1996,16(4):238-242.Zhao Huiyun,Li Wuling,Rao Yongqing,et al.Mutual comparison between several formulae used for estimating absorbed dose to tritiumincorporated cell nuclei[J].Chin J Radiol Med Prot,1996,16(4):238-242
估算含氚细胞核吸收剂量不同模式的相互比较
Mutual comparison between several formulae used for estimating absorbed dose to tritiumincorporated cell nuclei
投稿时间:1995-11-07  修订日期:1996-04-14
DOI:
中文关键词:  剂量模式的比较  氚核素  核吸收剂量估算
英文关键词:Cell nuclei  tritium  absorbed  dose estimation  formulae
基金项目:
作者单位
赵慧云 100083 北京, 北京医科大学放射医学基础教研室 
李五岭 100083 北京, 北京医科大学放射医学基础教研室 
饶用清 100083 北京, 北京医科大学放射医学基础教研室 
陈冠英 100083 北京, 北京医科大学放射医学基础教研室 
沈磊 100083 北京, 北京医科大学放射医学基础教研室 
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中文摘要:
      作者以3H-TdR掺入体外培养人淋巴细胞的实验资料, 用不同模式估算了细胞核的平均吸收剂量。结果表明, Robertson, Rossi和Goodheart法的结果基本一致。Apelgot法的结果偏高, 且对细胞核半径不敏感, 经适当调整后偏差降低, 对半径的敏感性提高。质量平均法的结果也较其他方法高。但对半径为3μm的细胞核, 经边缘效应校正后, 其结果与其他方法相近。0.27cGy/dis只对半径为4μm的细胞或细胞核有效, 不宜盲目应用。
英文摘要:
      The average absorbed dose to cell nuclei due to 3H-TdR incorporation in human lymphocytes was calculated by using different dose formulae on the basis of data obtained from incorporating experiments in vitro.The results showed that there was no significant difference between the nuclear doses estimated by the formulae of Robertson,Rossi and Goodheart.The results came from Apeigot's formula were higher than those from the above-mentioned formulae.A formula improved upon the Apelgot's was proposed.The "mass mean method" also brought about higher results,but by the aid of edge effect coefficient the method was able to give correct results for nuclei with 3μm radius.Ifthe radius of nuclei is larger or smaller than 3μm,abnormal results of mass mean method would emerge.The 0.27 cGy/dis.was just effective for nuclei with 4μm radius.
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