| 曹珍山,叶常青,袁丽珍,涂开成,樊飞跃,马柳芳,杨瑞彪,张仁元.大鼠胸部受到20Gyγ线照射后肺组织的形态计量学改变[J].中华放射医学与防护杂志,1996,16(3):167-169 |
| 大鼠胸部受到20Gyγ线照射后肺组织的形态计量学改变 |
| Morphometric changes of pulmonary tissues after 20Gy external irradiation of rat chest |
| 投稿时间：1995-03-21 修订日期：1995-07-14 |
| DOI： |
| 中文关键词: 形态计量学参数 20Gy γ线照射 肺组织 |
| 英文关键词:Morphometric parameters gamma irradiation pulmonary tissues |
| 基金项目: |
|
| 摘要点击次数: 2817 |
| 全文下载次数: 1565 |
| 中文摘要: |
| 作者通过形态计量学的方法, 测量肺局部经20Gyγ线照射后, 早期不同时间肺各项主要参数的变化。结果表明：照射7天后肺微动脉、微静脉管壁增厚, 管腔通透性指数(管腔面积/血管全面积)减小(P<0.05).对管壁厚度与管腔通透性指数的回归分析发现, 两者呈直线负相关(Y=1.38-0.198X+0.01X2,R=-0.919),表明管腔的缩小是由于管壁的增厚所致；受照15天后大鼠肺组织的肺泡壁厚度增厚；肺泡腔面积减小；肺间质面积增大(P<0.0l);电镜结果显示：微血管周围渗出严重；肺Ⅱ型细胞排空明显；肺组织中细胞种类、数量增多。 |
| 英文摘要: |
| The changes in the main parameters of the lungs at different periods of early stage after local 20Gy external irradiation of the lungs were measured with morphometric method.The results indicated that the walls of pulmonary arterioles and venules thickened and the vascular permeability index(area of vascuiar lumen/total area of blood vessel) decreased 7 days after irradiation(P<0.05).Regression analysis of the vascular wall thickness and the vascular permeability index revealed that the two parameters had negative correlation(Y=1.38-0.198X+0.01X2, r=-0.919), indicating that narrowing of the vascular lumen was the result of thickening of the vascular wall.Fifteen days after irradiation, the pulmonary alveolar wall thickened, the area of alveolar cavity decreased and the area of pulmonary interstitial space increased(P<0.01).Electronmicroscopic examination demonstrated profuse exudation surrounding the microvessels, obvious evacuation of pulmonary type-Ⅱcells and increase in cellular types and quantity of pulmonary tissues. |
| HTML 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|