| 叶本兰,程天民,肖家思.放射损伤、烧伤及放烧复合伤后血液动力学变化的实验研究[J].中华放射医学与防护杂志,1996,16(2):75-80.Ye Benlan,Cheng Tianming,Xiao Jiasi.Effects of radiation,burn and combined radiation-burn injury on hemodynamics[J].Chin J Radiol Med Prot,1996,16(2):75-80 |
| 放射损伤、烧伤及放烧复合伤后血液动力学变化的实验研究 |
| Effects of radiation,burn and combined radiation-burn injury on hemodynamics |
| 投稿时间：1995-01-10 修订日期：1995-04-28 |
| DOI： |
| 中文关键词: 放射损伤 烧伤 血液动力学 |
| 英文关键词:Radiation injury burn hemodynamic |
| 基金项目:全军八·五攻关课题 |
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| 中文摘要: |
| 作者研究了放烧复合伤后8小时以内的心脏血液动力学的动态变化及补液后的影响。结果如下：①放烧复合伤后早期休克较单纯烧伤者重。 |
| 英文摘要: |
| Changes in hemodynamics after radiation, burn and combined radiationburn injury within eight hours postinjury were studied. The results indicate: (1)Shock of rats in the combined injury group is more severe than that in the burn group.One of the reasons is that the blood volume in the combined injury group is less than that in the burn group.Radiation injury plays an important role in this effect,which enhances the increase in vascular permeability and causes the loss of plasma.(2) Decrease in cardiac output and stroke work and increase in vascular resistance in the combined radiationburn group are more drastic than those in the burn group, which may cause and enhance shock. Replenishing fluid is useful for recovery of hemodynamics.(3) Rb uptake is increased in the radiation group which indicates that compensated increase of myocardial nutritional blood flow may take place before the changes of hemodynamics and shock.Changes of Rb uptake in the combined injury group is different from that in the radiation group and in the burn group.The results also suggest that changes of ion channel activities may occur to a different extent after injury. (4) Verapamil is helpful to the recovery of hemodynamics post injury.It is better to combine verapamil with replenishing fluid. |
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