| 刘佩彬,王玉民,韦志康,徐琳.Licam促排238pu的实验研究[J].中华放射医学与防护杂志,1995,15(6):404-406 |
| Licam促排238pu的实验研究 |
| An experimental study on removal of 238Pu by Licam |
| 投稿时间：1994-09-27 修订日期：1995-02-21 |
| DOI： |
| 中文关键词: 螯合剂 Licam DTPA 促排238Pu |
| 英文关键词:Chelates Licam DTPA removal plutonium-238 |
| 基金项目: |
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| 中文摘要: |
| 用山东医大合成的三种Licam(S)及三种Licam(C)对238Pu中毒小鼠进行了早期促排试验(中毒后1小时、8小时促排2次).结果发现：对骨及肝内的钚有促排作用,但不及DTPA;在肾脏则明显增加滞留量,最高者可为盐水对照组的2.6倍,而且在16天内一直以高滞留状态逐渐下降。而DTPA促排后,肾钚则一直低于对照组。 |
| 英文摘要: |
| The effects of six chelating agents,i.e.three Licam(s)and three Licam (c) , obtained from Shandong Medical University,on clearing of 238Pu were intestigated in mice.At 1 and 8 hours after poisoning with 238Pu, these Licam chelates were given, respectivly.The results show that the Licam chelates are effective for removal of 238Pu from bones and liver, but less effective than DTPA.Increased retention of 238Pu in kidneys(up to 2.6 times that for the control group receiving saline solution)was seen with slow decrease during 16 days.In DTPA group,contents of 238Pu in kidneys were lower than those in the control group at all test times. |
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