| 赵永昌,陈如松,李茂河,王亚君.钚锶对大鼠复合作用的实验研究[J].中华放射医学与防护杂志,1990,10(4):235-238 |
| 钚锶对大鼠复合作用的实验研究 |
| Experimental study on combined effect of 239Pu and 90Sr on rats |
| 投稿时间：1988-02-08 |
| DOI： |
| 中文关键词: 钚 锶 辐射致癌 骨肉瘤 复合作用 |
| 英文关键词:combined effect 239P 90Sr osteosarcoma rats |
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| 中文摘要: |
| 本文探讨低剂量硝酸钚与硝酸锶对大鼠复合作用的实验研究。系统观察了体重、死亡率, 平均存活时间、X线片、病理组织学等项目指标的改变。通过三年左右的终生观察表明: (1)钚、锶复合作用对诱发骨肉瘤有相加效应, 并且潜伏期短, 多发性骨肉瘤也高于单一核素作用组, (2)复合作用组的死亡率高于单一核素组, (8)复合作用组的平均寿命比单一核素组缩短。 |
| 英文摘要: |
| This paper reports on the combined effect of 239Pu and 90Sr on rats. 210 Wistar rats Were equally divided into 5 groups, with 24 male and 18 female rats in each group：group A(contr01), group B(90Sr nitrate 200μtCi/kg, i·P), group C (239Pu nitrate 5μCi/kg, i·P), group D(239Pu and”Sr, i·P), and group E (treated same as D plus an exposure to 2 Gy γ-rays). Results indicated that the combined effects of 239Pu and 90Sr were larger than the respective effects of each： (1)the incidences of osteosarcoma for groups D and E were 64.3%and 57.1%, respectively, but for groups B and C were 31%and 42.9%only(for group A 0%).In addition, the time of appearance of induced osteosareoma、in groups D and E was earlier than that in groups B and Cl (2)the average life-span in groups D and E was obviously shorter than that in groups B and C;and(3)the mortality in groupsD and E was higher than that in groups B and C. |
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