| 郭力生,关首任,陈和义.放射性碘在甲状腺内的分布特点[J].中华放射医学与防护杂志,1981,1(6):14-19 |
| 放射性碘在甲状腺内的分布特点 |
| The Distributive Characteristics Of RadiOiOdine in ThyrOid Gland |
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| 中文摘要: |
| 由大鼠静脉注入碘-125后20秒或腹腔注入50秒,碘-125主要分布于上皮细胞内。当注入时间分别延长至1.5分和15分时,则浓集于滤胞腔内,并在该处长时间蓄留。它在甲状腺内分布很不均匀。甲基硫脲嘧啶(MTU)可明显减少甲状腺对碘-125的吸收量,并使滤胞上皮细胞肿大,但未影响碘-125在滤胞内的空间分布。在本条件下,未看出促甲状隙激素释放激素(TRH)改变碘-125在甲状腺内的吸收、分布特点。注入碘-125前4小时或同时服用碘化钾,可明显阻止碘-125在甲状腺内的沉积.但前者更理想;注入碘-125后4小时服碘化钾.效果很小。 |
| 英文摘要: |
| As shown by autoradiography,20 seconds after intravenous injection or 50 seconds after intraperitoneal injection of 125I to mice.125I was located mainly in the epithelial cells of thyroid follicles.At 1.5 and 15 minutes after injection 125I was concentrated in the cavity of the follicles and remained there for a long time. 125I was not evenly distributed in the thyroid gland. |
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