| 吴骋,王又明,陈小蘅.低剂量率60Coγ线长期慢性照射和一次急性照射雄性小鼠诱发显性致死突变的研究[J].中华放射医学与防护杂志,1981,1(4):1-7.Wu Cheng,Wang Youming,Chen Xiaoheng.A STUDY OF DOMINANT LE THAL MUTATION IN MICE INDUCED BY LOW DOSE RATE CHRONIC IRRADlATION AND SINGLE ACUTE IRRADIATION WITH 60COγ-RAY[J].Chin J Radiol Med Prot,1981,1(4):1-7 |
| 低剂量率60Coγ线长期慢性照射和一次急性照射雄性小鼠诱发显性致死突变的研究 |
| A STUDY OF DOMINANT LE THAL MUTATION IN MICE INDUCED BY LOW DOSE RATE CHRONIC IRRADlATION AND SINGLE ACUTE IRRADIATION WITH 60COγ-RAY |
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| 中文摘要: |
| 每天以2.02、3.84、7.68和13.03拉德γ线慢性照射雄性小白鼠,诱发的显性致死突变率均高于对照组。其中7.68和13.03拉德组的诱发率与累积剂量线性相关,分别为2.19×10-4/拉德和2.63×10-4/拉德。以114拉德/分剂量率一次照射小白鼠精子和精细胞的诱发率均与照射剂量呈线性相关,分别为0.75×10-3/拉德和1.49×10-3/拉德。慢性照射和急性照射精原细胞诱发的显性致死突变与累积剂量均无相关性。 |
| 英文摘要: |
| When male mice were exposed to chronic irradiation of 60Coγ-ray at daily dose of 2.02,3.84,7.68 and 13.03 md,the induced dominant lethal mutation rate among these animals was higher than that of the control.There was a linear relationship between tne dominant lethal and accumulative dose,especially,while animals had received a daily dose of 7.68 tad and 13.03 md.The dominant lethal mutation rates were 2.19×10-4/rad and 2.63×10-4/rad respectively. |
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